TLDR YH0618 helped reduce skin and nail problems and fatigue in chemotherapy patients.
The randomized controlled trial involving 214 participants demonstrated that the medicinal and edible decoction YH0618 significantly reduced chemotherapy-induced dermatologic toxicities, including nail discoloration, alopecia, and skin hyperpigmentation, without causing serious adverse effects. The study also found that YH0618 improved fatigue and quality of life over time, with significant improvements observed at 6 weeks. The findings suggested that YH0618 could be a promising intervention for managing chemotherapy-induced dermatologic toxicities and enhancing patients' overall well-being.
17 citations
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January 2019 in “Journal of cancer” The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
110 citations
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August 2014 in “International journal of cancer” Scalp cooling significantly reduces chemotherapy-induced hair loss.
3 citations
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November 2011 in “European Journal of Dermatology” 4-O-methylhonokiol from Magnolia officinalis significantly promotes hair growth.
155 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” Scalp cooling might reduce hair loss from chemotherapy, but evidence is weak and other treatments are being tested.
5 citations
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August 2025 in “Biomedicines” Early detection and multidisciplinary management of skin and mouth side effects from breast cancer treatments improve patient outcomes.
278 citations
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May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
2 citations
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October 2018 in “Springer eBooks” Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
179 citations
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October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
28 citations
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December 2006 in “Clinical lung cancer” Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.