Effect of a Medicinal and Edible Decoction YH0618 on Chemotherapy-Induced Dermatologic Toxicity: A Randomized Controlled Trial

    January 2021 in “ Annals of translational medicine
    Jie-Yu You, Yi He, Hui Zhi, Victor Ho-fun Lee, Suetmui Chan, Lixing Lao, Huan-lan Liu, Jianping Chen
    Studysummary This study found that the YH0618 decoction reduced chemotherapy-induced nail discoloration, alopecia, skin hyperpigmentation, and fatigue in cancer patients who completed chemotherapy. Our plain-language summary of this paper — not a Tressless recommendation.
    The randomized controlled trial involving 214 participants demonstrated that the medicinal and edible decoction YH0618 significantly reduced chemotherapy-induced dermatologic toxicities, including nail discoloration, alopecia, and skin hyperpigmentation, without causing serious adverse effects. The study also found that YH0618 improved fatigue and quality of life over time, with significant improvements observed at 6 weeks. The findings suggested that YH0618 could be a promising intervention for managing chemotherapy-induced dermatologic toxicities and enhancing patients' overall well-being.
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