Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the applications and potential of microneedles loaded with extracellular vesicles for tissue regenerative repair and disease diagnosis, but does not report new experimental findings.

This study in Saudi Arabia found that 59.70% of participants experienced hair shedding during or after COVID-19, with significant risk factors including being female, having a history of telogen effluvium, and receiving COVID-19 antiviral treatment.

This study concluded that the liquid chromatography-mass spectrometry method developed is viable for accurately quantifying spironolactone and its metabolite canrenone in plasma despite interference from plasma components.

This study reported the preparation of stable oil-in-water nanoemulsions that effectively incorporate ceramide-like molecules and minoxidil, suggesting these formulations may enhance distribution and availability of hydrophobic compounds in cosmetic applications.

This review summarizes clinical trials and comparative studies showing that latanoprostene bunod 0.024% is effective and safe for reducing intraocular pressure in patients with open-angle glaucoma or ocular hypertension, detailing its mechanism and side effects while considering its therapeutic role.

In this study, researchers developed a new self-administered finasteride delivery system using powder-carrying microneedles that improved hair growth efficacy and addressed safety concerns compared to topical finasteride gel by allowing sustained intradermal release of the drug for three days with a single application.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study examines the use of emulgel-based systems as drug delivery vehicles for hydrophobic medications, noting their potential benefits in dermatological applications due to properties like easy spreadability, non-greasy texture, and prolonged shelf life.

This study formulated a nanogel with Bangkal bark extract that showed moderate antibacterial activity against Propionibacterium acnes, with the F3 formulation (8% extract) achieving the highest inhibition zone of 8 mm, suggesting potential as a natural acne treatment.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

In this overview of COPD exacerbations, it was reported that these events, often triggered by respiratory viruses, not only worsen symptoms but also increase the risk of cardiac events, highlighting the importance of early detection and prevention strategies such as vaccinations and new biologic therapies.

This study on androgenetic alopecia in mice introduced a novel therapy combining microneedle patches and cold atmospheric plasma to enhance minoxidil delivery, leading to improved hair regeneration by boosting vascular growth and reshaping the hair follicle microenvironment.

A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, offering a cost-effective alternative to specialized medical containers.

This review discusses various topical medication instillation techniques for managing glaucoma but reports a lack of evidence on their effectiveness compared to usual care.

The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.

In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.

This study evaluated niosome-based gels for delivering salicylic acid topically to treat acne vulgaris and found that the formulation SANG5, using Carbopol 940 and nutmeg oil, demonstrated the best drug release profile.

In this study, early treatment with nitazoxanide, ivermectin, or hydroxychloroquine, combined with azithromycin, was associated with reduced hospitalizations, respiratory complications, and deaths in early-stage COVID-19 patients compared to untreated controls.

In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

New microneedle method improves hair regrowth treatment delivery.

This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.

This study developed a new suspended ointment formulation containing neomycin sulfate and triamcinolone acetonide, which showed promise for treating neurodermatitis and chronic eczema by ensuring stable composition, effective skin penetration, and no skin irritation.

A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, saving money for medical practitioners.

This study concluded that a liquid serum formulation delivered two fluorescent dyes to deeper follicular regions more effectively than nanoparticle systems.

This review highlights the potential of nanoemulgel as a promising drug delivery system for lipophilic drugs, but presents no new experimental results; it discusses composition, preparation methods, and applications.

This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.

A new treatment using special microneedles and a nitric oxide-releasing drug could improve hair growth and be more convenient for people with hair loss.