Nanoemulsions for the Encapsulation of Hydrophobic Actives

This study analyzed the use of oil-in-water nanoemulsions to encapsulate two hydrophobic actives: a ceramide-like molecule and minoxidil. The goal was to create stable, aqueous-based formulations to enhance the penetration of these compounds through cosmetic substrates. The nanoemulsions had droplet sizes around 200 nm and a negative surface charge, achieving stability without modification for several weeks. Formulations included up to 2% ceramide-like molecules and over 10% minoxidil. The study concluded that nanoemulsions were a promising tool for improving the distribution and availability of hydrophobic molecules in technological applications.