Remodel the Perifollicular Microenvironment via Minoxidil-Loaded Microneedle Patch and Cold Atmospheric Plasma for Treating Androgenetic Alopecia

    April 2024 in “ Nano research ”
    Hao Chen, Xianzhe Tang, Yewei Huang … Zhitong Chen
    Studysummary This study on androgenetic alopecia in mice introduced a novel therapy combining microneedle patches and cold atmospheric plasma to enhance minoxidil delivery, leading to improved hair regeneration by boosting vascular growth and reshaping the hair follicle microenvironment.
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    Research cited in this study 15

    1. Advances in Microneedles Research Based on Promoting Hair Regrowth Journal of Controlled Release · 2022
    2. Conditioned Media-Integrated Microneedles for Hair Regeneration Through Perifollicular Angiogenesis Journal of Controlled Release · 2022
    3. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    4. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    5. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth ACS nano · 2019
    6. Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness Nature Communications · 2018
    7. Transcutaneous Implantation of Valproic Acid-Encapsulated Dissolving Microneedles Induces Hair Regrowth Biomaterials · 2018
    8. Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase International Journal of Molecular Sciences · 2017
    9. Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness Nature communications · 2017
    10. Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells Nanomedicine: Nanotechnology, Biology and Medicine · 2015
    11. Promotive Effect of Topical Ketoconazole, Minoxidil, and Minoxidil with Tretinoin on Hair Growth in Male Mice ISRN Pharmacology (Print) · 2014
    12. Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata Pharmaceutical Research · 2012
    13. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    14. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    15. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001

    Related research 9

    1. Evaluation of the Effect of Topically Applied Methylsulfonylmethane and Their Combination with Minoxidil Solution for Improvement of Hair Growth in Male Mice Wiadomości lekarskie (Warsaw Poland) · 2022
    2. Deterioration of Scalp Environment by Exogenous Factors and Its Influence on Hair Growth Promoting Effect of Minoxidil The Pharmaceutical Society of Japan · 2020
    3. Effect of Minoxidil on Hair Growth in Minipigs Journal of Investigative Dermatology · 2018
    4. Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment Skin appendage disorders · 2015
    5. A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia Journal of clinical & experimental dermatology research · 2015
    6. Effects of Mixed Medicinal Herbal Extract on Hair Growth in Mice with Alopecia 2014
    7. Comparison of the Efficacy and Safety of Topical Minoxidil and Topical Alfatradiol in the Treatment of Androgenetic Alopecia in Women Journal der Deutschen Dermatologischen Gesellschaft · 2007
    8. A Study on Effects of Water-Soluble Minoxidil on Hair Growth in C57BL/6 Mice Strait Pharmaceutical Journal · 2007
    9. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002