research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
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research The Expanding Impact of T-Regulatory Cells in Skin Health
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome
A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.
research Current Management Strategies for Cutaneous T-Cell Lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long After Childbirth
Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Industry Updates from the Field of Stem Cell Research and Regenerative Medicine in June 2019
In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.
research Red Blood Cell Folate Level in Patients with Alopecia Areata
Red blood cell folate levels are reliable indicators of long-term folate status in alopecia areata patients.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Epigallocatechin-3-Gallate Inhibits Paclitaxel-Induced Apoptosis Through the Alteration of MicroRNA Expression in Human Dermal Papilla Cells
Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Genome-Wide Association Study of Skin Complex Diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Treatment Options for Alopecia: An Update, Looking to the Future
The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
research A Comparative Analysis of Immune Privilege in Pregnancy and Cancer in the Context of Checkpoint Blockade Immunotherapy
The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
research Contact Dermatitis to Phenol-Formaldehyde Resin in Two Plywood Factory Workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research Genomewide Differential Expression Profiling of Long Non-Coding RNAs in Androgenetic Alopecia in a Chinese Male Population
Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
research Current and Future Pharmacotherapy for Alopecia Areata
New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
research Thyroid Autoimmunity in Patients with Skin Disorders
People with alopecia areata often have thyroid autoimmunity.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.