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Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Finasteride helps brain function in rats with liver-related brain issues.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

M30 is a promising treatment for preventing hair loss during chemotherapy.

Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Finasteride may affect PNMT, causing side effects.

The document concludes that there is hope for future psychopharmacology research despite challenges in treating schizophrenia.

Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.

Monocyclic aromatic compounds are important for developing various drugs and treatments.

DHEA improved brain function and behavior in old monkeys and had additional health benefits.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Some medicinal plants can help heal wounds and may lead to new treatments.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.