Effect of Neurosteroid Dehydroepiandrosterone on the Higher Nervous Activity of Old Non-Human Primates

March 2014 in “ Human Physiology ”

Н. П. Гончаров, G. V. Katsiya, A. A. Dzhokua, V. S. Barkaya, Z. V. Kulava, Z. Ya. Mikvabiya

dehydroepiandrosterone DHEA hair restoration

TLDR DHEA improved brain function and behavior in old monkeys and had additional health benefits.

The study from 2014 examined the impact of dehydroepiandrosterone (DHEA) on the higher nervous activity and behavior of five old male rhesus macaques, aged 24-30 years. The macaques were given DHEA intramuscularly at a dose of 1 mg/kg every two days for three months. The results showed that DHEA improved higher nervous activity, increased motor activity and alimentary motivation, and balanced excitatory and inhibitory processes in the brain. Notably, DHEA also led to the restoration of lost hair cover in the monkeys, an effect that lasted for a year post-treatment. The study concluded that DHEA could be effective for medical correction of higher nervous activity in old monkeys and has multiple beneficial effects, including neuron survival and reduced cell apoptosis.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 864 upvotes 4 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 16 months finasteride progress but slowly losing hair again

in Progress Pictures 140 upvotes 3 weeks ago

A 21-year-old male experienced initial success with finasteride for 16 months but is now losing hair again. He is considering switching to dutasteride and adding oral minoxidil, while also investigating environmental and health factors.

community Please take a vitamin & hormone test

in Chat 256 upvotes 2 months ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

community Cardio for more than 60 minutes reduces DHT levels and improve hair growth

in Research/Science 126 upvotes 1 week ago

Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hair growth.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

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