6 citations,
December 2022 in “Cell reports” Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
14 citations,
August 2021 in “Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy” Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
May 2022 in “Cardiovascular Toxicology”
3 citations,
July 2022 in “Problemy èndokrinologii” Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
9 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
1 citations,
November 2011 in “British journal of pharmacology” Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
9 citations,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
9 citations,
March 2022 in “Frontiers in Immunology” Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
71 citations,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
September 2019 in “Journal of Investigative Dermatology” Silibinin may help promote hair growth and treat hair loss.
November 2018 in “Atlas of genetics and cytogenetics in oncology and haematology” WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
47 citations,
December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
January 2023 in “Czech Journal of Animal Science” Proteins influence the quality and traits of cashmere goat fleece, affecting hair strength and diameter.
July 2023 in “Biomolecules” The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
10 citations,
June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
88 citations,
April 2017 in “Journal of Pediatric and Adolescent Gynecology” The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.
10 citations,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
19 citations,
January 2018 in “BioMed Research International” miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
44 citations,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
June 2023 in “Medical records-international medical journal” Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
1 citations,
August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
11 citations,
January 2000 in “Journal of Cutaneous Pathology” Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
26 citations,
May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
159 citations,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.