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This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.

This review details the advancements and benefits of fractional erbium:YAG resurfacing lasers for treating photoaging, acne scarring, and dyschromia, but it presents no new clinical results.

This study found that conditioned media from epidermal progenitor cells improved skin aging signs in a clinical trial and protected fibroblasts from oxidative stress in vitro.

This review discusses the effectiveness of non-thermal, non-ablative devices like light-emitting diodes in treating various skin and hair conditions but reports no new clinical findings.

In this study, combining microneedle and sublative fractional radiofrequency treatments significantly improved skin tightening, texture, collagen organization, and satisfaction in individuals with moderate photoaging, while reducing abnormal elastin after three months.

This study found that mesenchymal stem cells mainly promote skin regeneration and delay aging through paracrine activity, releasing growth factors and cytokines that protect against oxidative stress and stimulate healing.

In this study, researchers developed iron-curcumin-coordinated nanoparticles to enhance curcumin's bioavailability and therapeutic effects, finding that these nanoparticles accelerate wound healing in diabetic mice by reducing inflammation and oxidative stress more effectively than free curcumin.

This systematic review found that exosome-based therapies significantly improve skin elasticity, reduce wrinkle depth, enhance hydration, and modulate pigmentation, with minimal adverse events reported across multiple studies. However, further clinical trials are necessary to confirm long-term efficacy and safety.

The hydrogel helps heal wounds without scars by releasing two drugs gradually.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.

This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.

This review evaluated current evidence on minoxidil's potential to treat scars and reported reduced collagen accumulation and fibrosis in various studies, suggesting its antifibrotic effects may benefit wound healing; however, direct studies on acne scars are yet to be conducted.

This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.

In this study, a silk fibroin hydrogel containing recombinant NT3 was found to promote scar-less wound healing in a mouse skin injury model by enhancing type III collagen expression and inducing hair follicle formation.

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

In this mouse study, researchers found that orally administered low-molecular-weight fish collagen peptides significantly improved hair regrowth by both enhancing growth-promoting pathways and reducing inhibitory mechanisms.

This study reported that fermented yeast complex extract may promote hair regrowth by modulating antioxidative and anti-inflammatory pathways in dermal papilla cells and increasing hair follicle numbers in an animal model.

This research explores the potential of Gel-SHP hydrogels in tissue regeneration, suggesting they could contribute to new methodologies and understanding in wound healing and dermal shell formation, but results are not detailed.

This study provides a detailed cellular atlas of cutaneous squamous cell carcinoma, indicating that different fibroblast subtypes play roles in tumor progression and suppression, with potential biomarkers identified for HPV-related tumor growth.

This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.

This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.

In this study, APC collagen peptides were observed to enhance hair elasticity and gloss in human hair follicles by increasing amino acid and lipid component levels, suggesting their potential benefits for improving hair qualities.

This review reports that oral collagen peptide supplements may improve skin elasticity, hydration, and wrinkle appearance while also supporting hair and nail health and wound healing, but emphasizes the need for longer, high-quality studies due to current research limitations and variability in findings.

In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

In this study, around 1% of proteins in skin fibroblasts significantly changed in response to reductive stress, affecting collagens and MAPK signaling pathways.

This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.

This study explores the complex mechanisms of skin aging, including cellular senescence and disrupted communication, and highlights rejuvenation strategies like gene expression rewiring and microbiome modulation, offering potential frameworks for regenerative therapies and precise interventions in skin and systemic aging.