Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

    March 2026 in “ Calcified Tissue International ”
    Ehsan Pashay Ahi, Jacqueline Moustakas-Verho, Pooja Singh
    Studysummary This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 5

    1. Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3 Nature Communications · 2019
    2. XEDAR Activates the Non-Canonical NF-κB Pathway Biochemical and Biophysical Research Communications · 2015
    3. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update Journal of Dermatological Science · 2012
    4. Ectoderm-Targeted Overexpression of the Glucocorticoid Receptor Induces Hypohidrotic Ectodermal Dysplasia Endocrinology · 2005
    5. Stimulation of Ectodermal Organ Development by Ectodysplasin-A1 Developmental Biology · 2003