Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress

    December 2025 in “ Antioxidants ”
    Kyung-A Byun, Chang Hu Choi, Seyeon Oh, Jimin Hyun, Kuk Hui Son, Kyunghee Byun
    Image of study
    TLDR Fermented Yeast Complex Extract helps regrow hair by reducing oxidative stress and inflammation.
    The study investigates the effects of Fermented Yeast Complex Extract (FYCE) on hair regrowth, focusing on its ability to modulate oxidative stress and inflammation in dermal papilla cells (DPCs) treated with hydrogen peroxide. FYCE significantly increased NRF2 expression, a key antioxidant defense factor, and suppressed NF-κB activity, a mediator of inflammation. It also reduced NLRP3 inflammasome activation and increased levels of IGF-1, Wnt10b, Wnt3a, and stabilized β-catenin, which are important for hair growth. In animal models, FYCE increased hair follicle numbers and prolonged the anagen phase. These results suggest FYCE as a potential treatment for hair loss by promoting hair regrowth through antioxidative and anti-inflammatory pathways.
    Discuss this study in the Community →

    Research cited in this study

    25 / 25 results

    Related Community Posts Join

    6 / 22 results

      community Anyone here going the “natural” route?

      in Scalp Massage  48 upvotes 3 years ago
      People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.

      community Scalp, eyebrow, eyelash and pubic hair loss.

       7 upvotes 7 years ago
      The user experienced significant hair loss on the scalp, eyebrows, eyelashes, and pubic area, along with itchy, flaky skin and red patches. They have a history of eczema and dermatitis and suspect that stopping shampoo use and taking Ritalin may have contributed to the issue.

      community Fermented Rice Water ..... ???

      in Treatment  112 upvotes 2 years ago
      User discusses Fermented Rice Water as a hair loss treatment, with one person claiming it helped regrow their hair. Others share their experiences and opinions, with some skepticism and alternative explanations.

      community I cant believe its actually working…

      in Finasteride/Dutasteride  25 upvotes 1 month ago
      The user experienced significant hair regrowth using 1mg oral finasteride, DIM, and beetroot powder, while also focusing on gut health and reducing alcohol intake. Other users discussed the importance of iodine, fermented foods, and maintaining a balanced diet for overall health and hair improvement.

    Similar Research

    5 / 448 results