January 2014 in “Journal of Tissue Engineering and Reconstructive Surgery” This study found that rabbit hair follicle stem cells, combined with electro-spun nano silk fibers, successfully constructed a tissue-engineered urethra, suggesting potential for future in vivo repair studies.
31 citations
,
May 2019 in “Nature communications” This study found that Blimp1+ cells from mice can generate sebaceous gland organoids in vitro, which mimic natural gland traits and may aid in studying acne vulgaris.
425 citations
,
August 2002 in “BioEssays” This review discusses the structure and assembly of the cornified cell envelope in stratified squamous epithelial cells and various disorders leading to barrier defects, but reports no new findings.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
116 citations
,
April 1986 in “The journal of cell biology/The Journal of cell biology” This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.
June 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.
This study found that the Padina arborescens extract and its component MOGG may prevent hair loss by inhibiting 5α-reductase activity, promoting cell proliferation, opening the KATP channel, and increasing PGE2 production in laboratory settings.
13 citations
,
June 2020 in “Stem Cells International” In this study using a mouse model, ECM/SVF-CM, derived from adipose-derived stem cells, was observed to stimulate hair growth more effectively than SVF-CM by promoting cell proliferation, neovascularization, and anagen induction, which may support its potential as an improved treatment for hair loss.
September 2026 in “Repository of the University of Ljubljana (University of Ljubljana)” This study analyzed hair styling mousses on the Slovenian market, finding that their formulations primarily rely on polymers, with no banned ingredients according to European cosmetics regulations.
324 citations
,
May 2002 in “Oncogene”
9 citations
,
October 2021 in “Biological and Pharmaceutical Bulletin” This study found that mupirocin nanoparticle-loaded hydrogel was safe and more effective for healing burn wounds in rats compared to mupirocin ointment, showing promise for future clinical trials.
3 citations
,
June 1979 in “The Journal of Dermatology” This study found that the dermal glycosaminoglycan content and mast cell count in rats peaked during the anagen stage of hair growth and decreased during later stages.
1 citations
,
November 2023 in “Biomaterials advances” This study found that combining mesenchymal stromal cells from adipose tissue and hair follicles with soy protein and β-chitin scaffolds significantly reduced wound healing time and improved skin regeneration in vivo.
46 citations
,
January 1991 in “Tissue and Cell” This study observed that during male silkmoth development, trichogen cells in olfactory sensilla undergo significant membrane recycling, contributing to sensillum structure formation in a precisely timed series of stages.
33 citations
,
July 2007 in “Journal of cell science” This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.
40 citations
,
January 2022 in “Frontiers in Chemistry” This study found that a microneedle array patch using a blend of kangfuxin, chitosan, and fucoidan significantly accelerated wound healing in rats by enhancing epithelial thickness and collagen deposition.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” This article reviews the potential advantages of secretome derivatives from human uterine cervical stem cells in MSC therapy and notes the need for regulatory standards to ensure safety and efficacy.
2 citations
,
August 2022 in “Viruses” This study found that cutaneous squamous cell carcinomas in mice infected with murine papillomavirus preferentially arise from Lgr5+ progenitor cells, while squamous cell dysplasia does not.
48 citations
,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.
18 citations
,
February 1992 in “Molecular Biology Reports” This study identified and characterized a murine type II hair keratin, demonstrating its presence in specific cells of hair and tongue tissues.
6 citations
,
July 2025 in “Advanced Materials” This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.
April 2024 in “Molecules/Molecules online/Molecules annual” The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.
36 citations
,
January 2004 in “European journal of cell biology” This study found that in mice, deleting the keratin 10 gene enhances sebocyte differentiation and increases secretion of sebum and certain lipids without affecting proliferation-associated keratins.
57 citations
,
August 1997 in “Microscopy Research and Technique” This review discusses novel molecular techniques in skin appendage research and summarizes the distribution of key molecules, but it reports no new experimental results.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
15 citations
,
January 2021 in “Journal of Materials Chemistry B” In this study, shear-thinning silk nanofiber hydrogels were found to enhance retention of mesenchymal stem cells and accelerate wound healing in rat models.
September 2026 in “Mendeley Data” This study found that a polyurethane-cellulose acetate scaffold with plasma rich in growth factors may enhance gene expression related to wound healing in an experimental setting.
November 2016 in “Oncology Letters” This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.
12 citations
,
July 1993 in “In Vitro Cellular & Developmental Biology - Animal” Minoxidil enhances hair growth and preserves the root sheath in cultured follicles.
86 citations
,
March 2018 in “ACS Biomaterials Science & Engineering” This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.