Molecular Histology in Skin Appendage Morphogenesis
August 1997
in “
Microscopy Research and Technique
”
TLDR New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
Classical histological studies had revealed the cellular organization of skin appendages, but the molecular bases of their morphogenesis and histogenesis were less understood. Recent molecular biological approaches identified many new molecules expressed specifically during skin appendage formation. This review discussed novel molecular techniques and summarized the distribution of various molecules, such as growth factors and homeobox genes, using feather and hair models. The findings aimed to refine the understanding of skin appendage development and aid in forming new hypotheses and experimental designs, potentially influencing future healing and regeneration treatments.
