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    Glossary Homeobox Genes

    regulatory genes controlling body plan and organ development

    Homeobox genes, often referred to as Hox genes, are a group of regulatory genes that play a crucial role in determining the body plan and the formation of tissues and organs during early embryonic development. They contain a specific DNA sequence called the homeobox, which encodes a protein domain (the homeodomain) that can bind to DNA and regulate the expression of other genes. This precise regulation ensures that body structures form in the correct locations.

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    1. Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2 Journal of Investigative Dermatology · 1999 · 49 citations
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Altered Skin Wound Healing in Homeobox Gene Msx-2 Knockout Mice Wound Repair and Regeneration · 2008
    3. A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11 Genomics · 1989 · 49 citations
    4. Association between DNA Methylation in the Core Promoter Region of the CUT-like Homeobox 1 (CUX1) Gene and Lambskin Pattern in Hu Sheep Genes · 2023 · 1 citations
    5. Structure and expression of the ovine Hoxc-13 gene Gene · 2003 · 12 citations
    6. Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats 2023
    7. Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora goats Research Square (Research Square) · 2022
    8. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    9. Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis 2024
    10. Molecular histology in skin appendage morphogenesis Microscopy Research and Technique · 1997 · 57 citations
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