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GlossaryHomeobox Genes

regulatory genes controlling body plan and organ development

Homeobox genes, often referred to as Hox genes, are a group of regulatory genes that play a crucial role in determining the body plan and the formation of tissues and organs during early embryonic development. They contain a specific DNA sequence called the homeobox, which encodes a protein domain (the homeodomain) that can bind to DNA and regulate the expression of other genes. This precise regulation ensures that body structures form in the correct locations.

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Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

9 citations , May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.

research Structure and expression of the ovine Hoxc-13 gene

12 citations , December 2003 in “Gene”

The ovine Hoxc-13 gene is crucial for hair formation and may have other skin functions.

research Molecular Histology in Skin Appendage Morphogenesis

57 citations , August 1997 in “Microscopy Research and Technique”

New molecules involved in skin and hair growth were identified, improving understanding and future treatments.

Identification of Differentially Expressed Genes Affecting Hair and Cashmere Growth in the Laiwu Black Goat by Microarray

research Identification of Differentially Expressed Genes Affecting Hair and Cashmere Growth in the Laiwu Black Goat by Microarray

4 citations , September 2016 in “Molecular Medicine Reports”

Specific genes influence hair and cashmere growth in Laiwu black goats.

A Preliminary Study of Differentially Expressed Genes in Expanded Skin and Normal Skin: Implications for Adult Skin Regeneration

research A Preliminary Study of Differentially Expressed Genes in Expanded Skin and Normal Skin: Implications for Adult Skin Regeneration

16 citations , January 2011 in “Archives of Dermatological Research”

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

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