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GlossaryHomeobox Genes

regulatory genes controlling body plan and organ development

Homeobox genes, often referred to as Hox genes, are a group of regulatory genes that play a crucial role in determining the body plan and the formation of tissues and organs during early embryonic development. They contain a specific DNA sequence called the homeobox, which encodes a protein domain (the homeodomain) that can bind to DNA and regulate the expression of other genes. This precise regulation ensures that body structures form in the correct locations.

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research Structure and Expression of the Ovine Hoxc-13 Gene

12 citations , December 2003 in “Gene”

The ovine Hoxc-13 gene is crucial for hair formation and may have other skin functions.

Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

9 citations , May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.

Hoxc13 Mutant Mice Lack External Hair

research Hoxc13 Mutant Mice Lack External Hair

245 citations , January 1998 in “Genes & Development”

Hoxc13 gene is essential for hair, nail, and papilla development.

research Molecular Histology in Skin Appendage Morphogenesis

57 citations , August 1997 in “Microscopy Research and Technique”

New molecules involved in skin and hair growth were identified, improving understanding and future treatments.

Identification of Differentially Expressed Genes Affecting Hair and Cashmere Growth in the Laiwu Black Goat by Microarray

research Identification of Differentially Expressed Genes Affecting Hair and Cashmere Growth in the Laiwu Black Goat by Microarray

4 citations , September 2016 in “Molecular Medicine Reports”

Specific genes influence hair and cashmere growth in Laiwu black goats.

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