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GlossaryDlx3

gene crucial for hair follicle and skin development

Dlx3 is a gene that plays a crucial role in the development and differentiation of hair follicles, skin, and teeth. It is part of the Distal-less homeobox (Dlx) family of transcription factors, which are essential for regulating the expression of other genes during embryonic development. Mutations in Dlx3 have been linked to conditions such as Tricho-Dento-Osseous (TDO) syndrome, which affects hair, teeth, and bone development.

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research Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling

132 citations, August 2008 in “Development”

Dlx3 is essential for hair growth and regeneration.

research Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene

17 citations, May 2012 in “Journal of biological chemistry/The Journal of biological chemistry”

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

research Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle

149 citations, June 2010 in “The FASEB journal”

miR-31 regulates hair growth by controlling gene expression in hair follicles.

research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes

11 citations, August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Epithelial Differentiation

research DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Epithelial Differentiation

3 citations, January 2023 in “Science advances”

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

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