Search
for

    Glossary Dlx3

    gene crucial for hair follicle and skin development

    Dlx3 is a gene that plays a crucial role in the development and differentiation of hair follicles, skin, and teeth. It is part of the Distal-less homeobox (Dlx) family of transcription factors, which are essential for regulating the expression of other genes during embryonic development. Mutations in Dlx3 have been linked to conditions such as Tricho-Dento-Osseous (TDO) syndrome, which affects hair, teeth, and bone development.

    Sort by

    Research 30 of 135

    1. Dlx3 is a crucial regulator of hair follicle differentiation and cycling Development · 2008 · 132 citations
    2. Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Research · 2002 · 79 citations
    3. Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene 2012 · 17 citations
    4. Roles for Msx and Dlx homeoproteins in vertebrate development Gene · 2000 · 234 citations
    5. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    6. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    7. CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis Journal of Investigative Dermatology · 2013 · 9 citations
    8. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation Science advances · 2023 · 3 citations
    9. Human basal cell carcinoma: the induction of anagen hair follicle differentiation Clinical and experimental dermatology · 2019 · 3 citations
    10. Integrated transcriptomic and proteomic analysis reveals molecular mechanisms of melatonin-regulated hair follicle growth in cashmere goats and comparative insights across goat breeds BMC Genomics · 2025
    11. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation 2023
    12. 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion 2022
    13. Genome-wide expression profile analysis of 3D cultured dermal papilla cells from patients with androgenic alopecia Chinese Journal of Dermatology · 2014
    14. 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth 2023
    15. 723 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and three-dimensional chromatin topology in lineage-specific loci to control hair growth 2022
    16. 521 Deciphering Pathomechanisms in Solar Urticaria Journal of Investigative Dermatology · 2022
    17. Genetics underlying phenotypic diversity in South African sheep breeds Small Ruminant Research · 2025 · 2 citations
    18. An animal study on the effectiveness of platelet-rich plasma as a direct pulp capping agent Scientific Reports · 2024 · 4 citations
    19. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005 · 417 citations
    20. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014 · 223 citations
    21. MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway Journal of Cell Biology · 2014 · 103 citations
    22. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles PLOS Biology · 2018 · 68 citations
    23. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    24. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    25. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    26. To grow or not to grow: Hair morphogenesis and human genetic hair disorders Seminars in Cell & Developmental Biology · 2013 · 43 citations
    27. Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs Scientific Reports · 2016 · 34 citations
    28. Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity Developmental Biology · 2008 · 28 citations
    29. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    30. Unraveling the Molecular Mechanisms of Hair and Nail Genodermatoses Archives of Dermatology · 2001 · 23 citations