3 citations
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January 2021 in “Oxidative Medicine and Cellular Longevity” In this study, Nrf-2-expressing hair follicle mesenchymal stem cells showed the most significant therapeutic effect in a rat model of ulcerative colitis, suggesting a new potential treatment for the disease.
694 citations
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April 2000 in “Nature genetics” This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.
11 citations
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August 2021 in “Stem Cell Research & Therapy” This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.
16 citations
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June 1992 in “PubMed” In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.
15 citations
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August 2022 in “The Application of Clinical Genetics” This review describes the clinical presentation, diagnosis, and management of adrenomyeloneuropathy, including rehabilitative therapies and spasticity management, and reports no new clinical results.
4 citations
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August 2023 in “Frontiers in Pediatrics” This study observed that children with multisystem inflammatory syndrome associated with COVID-19 exhibited physical intolerance and fatigue shortly after the acute phase, but significant improvements in exercise capacity, laboratory markers, and cardiac health were reported by six months post-discharge.
1 citations
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July 2025 in “Journal of Human Immunity” This study found that administering minoxidil and PGE2 to pregnant mice with 22q11.2 deletion syndrome models corrected multiple developmental anomalies, including thymus growth and parathyroid positioning, by targeting prenatal mesenchymal differentiation.
In this case report, a young female who unintentionally ingested topical minoxidil experienced severe circulatory shock and acute pulmonary edema, emphasizing the need for immediate treatment with fluid resuscitation and vasopressors.
67 citations
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August 2007 in “American Journal of Pathology” This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.
5 citations
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April 2020 in “Journal of Mind and Medical Sciences” This review discusses underactive bladder, highlighting its poorly understood nature, diagnostic challenges, and limited treatment effectiveness, and reports no new clinical results.
September 2024 in “The Neurohospitalist” Careful management of chronic hyponatremia is crucial to prevent severe neurological issues.
January 2010 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This study found indications of phosphorus-calcium exchange abnormalities in children with chronic renal disease before kidney insufficiency, suggesting that early diagnostic methods like ultrasonic osteodensitometry could be beneficial.
36 citations
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July 2014 in “Neuromuscular Disorders” This study investigated a patient with spinal and bulbar muscular atrophy who had 68 CAG repeats, revealing early onset and unique symptoms not previously documented in the condition.
48 citations
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June 2014 in “Neurobiology of Disease” This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.
May 2018 in “The Journal of Immunology” In this study, daily treatment with angiotensin (1-7) significantly reduced disease severity in a mouse model of Systemic Lupus Erythematosus, suggesting potential for Mas agonists in future therapies.
54 citations
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December 2011 in “American Journal Of Pathology” This study found that immune-mediated destruction of bulge stem cells is a key factor in the alopecia observed in AE mice, suggesting it as a model for studying primary cicatricial alopecias, particularly lichen planopilaris.
January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
May 1985 in “The Pediatric Infectious Disease Journal” This report describes a case of a patient with Sjogren's syndrome who experienced multiple episodes of aseptic meningitis linked to taking trimethoprim-sulfamethoxazole and trimethoprim alone.
3 citations
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May 1994 in “Journal of Pharmacology and Experimental Therapeutics” This study found that minoxidil sulfate stimulates Cl channels, potentially depolarization-activated and outwardly rectifying, in eccrine clear cells, while minoxidil itself stimulates Ca-insensitive K currents.
49 citations
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December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
November 2024 in “Rheumatology Advances in Practice” This case report highlights the significance of alopecia totalis and knuckle pad hyperpigmentation as early indicators of azathioprine-induced myelosuppression and pancytopenia.
1 citations
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June 2025 in “Journal of Veterinary Internal Medicine” In this case study, a miniature donkey with multisystemic eosinophilic epitheliotropic disease was euthanized due to laminitis despite treatment for pruritus, inappetence, hypertriglyceridemia, and alopecia.
January 2026 in “International Journal of Applied Pharmaceutics” This study developed a novel LC-ESI-MS/MS method to quantify Minoxidil in pharmaceutical forms, finding it precise, accurate, and robust. It withstands excipient and degradant interference, although Minoxidil degrades under some stress conditions but remains stable thermally.
May 2023 in “International Journal of Molecular Sciences” This review highlights the complications of radiation therapy, specifically radiation cystitis, and explores the potential of mesenchymal stem cell-based therapies for tissue repair while discussing their therapeutic potential and limitations.
May 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study identified interactions between Vitamin D and Msx1 regulation pathways, noting that Msx1 overexpression decreases Vitamin D receptor expression in odontoblastic cells.
July 2025 in “Ultrasound in Medicine & Biology” This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.
7 citations
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March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
7 citations
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January 2017 in “Neuromuscular Disorders” This report documents the first adult onset case of Satoyoshi syndrome in South America, highlighting possible improvement with immunosuppressive treatment using corticosteroids and azathioprine.
1 citations
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January 2014 in “Indian journal of dermatology, venereology, and leprology” Papular mucinosis can cause eyebrow hair loss, but treatment can lead to regrowth.
January 2024 in “Wiadomości Lekarskie” In this study, a child's diagnosis of Silver-Russell syndrome was confirmed through phenotype data, genetic testing, and the exclusion of other developmental conditions, revealing a need for a multidisciplinary care approach.