Cavitating Osmotic Demyelination Syndrome Following Correction of Chronic Hyponatremia in Sheehan’s Syndrome: A Novel Case Report

This case report details a 40-year-old woman with Sheehan’s syndrome who developed cavitating osmotic demyelination syndrome (ODS) following the correction of chronic hyponatremia. The patient, initially misdiagnosed with psychiatric disorders, presented in a comatose state and was found to have severe hyponatremia and hypopituitarism. Despite treatment, her condition worsened, leading to the progression from extrapontine myelinolysis to central pontine myelinolysis. This case underscores the risks of even gradual correction of hyponatremia in chronic conditions and highlights the diagnostic challenges in low-resource settings.