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This study suggests that Keratin 15 expression in stratified epithelia may be regulated by two distinct mechanisms involving PKC/AP-1 pathway for differentiation and FOXM1 for basal cells, challenging its reliability as a sole stem cell marker.

This study found that humanized mouse models expressing mutated or reduced levels of the vitamin D receptor were able to maintain normal mineral homeostasis and prevent typical symptoms of vitamin D resistance.

This study found that testosterone increased the expression of AQP-1, 5, and 7 in the uterus of rats, which may help explain the reduction in uterine fluid volume.

This study found that treatment with the GnRH agonist Triptorelin significantly decreased invasion and expression of S100A4 and CYR61 in certain breast cancer cells, suggesting a potential role in slowing cancer progression.

This study found that inhibiting AP1 transcription factor activity in the suprabasal epidermis of mice alters keratinocyte gene expression, reducing barrier integrity and mimicking human keratoderma.

This study suggests that Flightless I may inhibit the activation of epidermal stem cells during wound repair by disrupting Wnt/β-catenin signaling, potentially delaying wound reepithelialization.

This study found that lower expression of VDR protein in breast cancer patients is associated with increased bone metastasis and poorer prognosis, making it a significant prognostic factor.

This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.

In this study, Oligonol® was shown to regulate gene expression related to cell proliferation and inflammation in human dermal papilla cells.

In this study on cultured human dermal papilla cells, researchers found that niacinamide may enhance hair growth by reducing oxidative stress-induced cell senescence and delaying catagen entry, suggesting potential applications against hair loss.

This review discusses the advancements needed for gene therapy to become commonly used in dermatology and reports no new clinical results.

The researchers reported that adenosine increases FGF-7 expression in dermal papilla cells, which may stimulate hair growth via the A2b adenosine receptor and cAMP pathway.

This review observes higher ACE2 expression in myocardial and lung tissues of heart failure and COPD patients but finds no link between RAAS inhibitors and COVID-19 severity.

This study found that expression of GDNF and GFR α-1 proteins in human skin decreases with age, particularly in the epidermis, suggesting that their signaling pathways may be altered as people grow older.

In this study, researchers evaluated the hair growth-promoting effects of strawberry water-extract on human follicle dermal papilla cells and found it enhanced cell metabolism, though it did not significantly alter hair growth-related gene expression.

miR-155-5p can help diagnose and track alopecia areata severity.

In this study, researchers analyzed skin tissue from two sheep breeds during the growing period and identified 56 differentially expressed lncRNAs and 616 mRNAs linked to hair follicle development, suggesting potential targets for improving sheep wool quality through genetic and molecular approaches.

This study investigated the role of the ABCA4 gene in human keratinocytes and hair follicle stem cells and found that silencing the ABCA4 gene increases the harmful effects of all-trans-retinal on hair follicle stem cells.

This study suggests that type I 5-alpha reductase may also play a role in hair growth, with dutasteride potentially being more potent than finasteride in modulating key hair growth gene expressions.

This study reported a significant upregulation of VEGF, which may help explain the beneficial effects of Ro on wound healing and hair loss, although further in-vitro and in-vivo studies are needed to better understand its molecular mechanisms and potential applications for skin disorders.

This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.

GLI2 activates GLI1, promoting skin tumor growth and hair development.

This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.

This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.

This study found that administering an adenovirus vector to increase Sonic hedgehog gene expression in mouse skin accelerated the transition of hair follicles into the growth phase, promoting hair growth.

This study found that cyclosporin A stimulates growth in cultured murine hair epithelial cells and reduces protein kinase C expression, suggesting that these actions may contribute to its hair-growing effects.

This study found that platelet factor 4 in platelet-rich plasma suppresses human hair follicle growth and alters related gene expressions, suggesting potential implications for its use in hair loss treatment.

This study found that cucurbitacin cream reduced FGF18 levels and accelerated hair follicle transition to the anagen phase in mice, suggesting its potential as a treatment for hair regeneration.