1 citations
,
July 2023 in “Nature communications” This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.
2 citations
,
August 2019 in “Turkish Journal of Chemistry” This study reported that CoFe2O4 magnetic nanoparticles efficiently catalyzed the synthesis of minoxidil from 2,6-diamino-4-chloro-pyrimidine N-oxide, achieving a 95% yield with sustained reusability.
29 citations
,
January 2017 in “Journal of Investigative Dermatology” This study found that increased MSI2 expression in hair follicle stem cells can delay hair growth by maintaining stem cell quiescence and repressing Hedgehog signaling.
1 citations
,
January 2022 in “Brazilian Journal of Pharmaceutical Sciences” This study investigated the physicochemical properties of polystyrene-b-poly(acrylic acid) nanovesicles coated with modified chitosans, finding that they can effectively control surface charge and potentially serve as drug delivery carriers with a 50.7% encapsulation efficiency for minoxidil.
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
3 citations
,
February 2025 in “Metabolites” In this study, researchers identified specific Se6OMT enzymes in *S. epigaea* involved in the cepharanthine biosynthetic pathway, providing insights into their substrate promiscuity and essential genetic components for metabolic engineering and synthetic biology applications of cepharanthine production.
5 citations
,
September 2018 in “Bioscience, Biotechnology, and Biochemistry” In this study, sodium thiosulfate was observed to promote hair growth in mice by encouraging hair follicles to enter the growth phase and complementing the effects of minoxidil, suggesting potential benefits for hair loss treatment.
August 2025 in “Stem Cells” This study developed a molecular systems architecture to map the complex interactions between mesenchymal stromal cells and their microenvironment, providing a framework for future predictive models that could enhance therapeutic strategies and reduce adverse effects.
36 citations
,
January 1994 in “Cell and Tissue Research” 20 citations
,
February 2017 in “European journal of pharmaceutical sciences” This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.
January 2025 in “Journal of Materials Chemistry B” 16 citations
,
May 1995 in “Biochemical and Biophysical Research Communications” In this study, researchers found that both thermolabile and thermostable forms of phenol sulfotransferase contribute to the sulfation of minoxidil, emphasizing the need to consider both enzymes in assessing sulfation in human tissues.
July 2026 in “Organoid Research” This review focuses on hydrogel microsphere-mediated strategies to improve organoid culture by addressing deficiencies in extracellular matrix organization, potentially enhancing the physiological accuracy and clinical translatability of osteomuscular in vitro models as reported in this study.
December 2025 in “Brazilian Journal of Chemical Engineering”
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.
4 citations
,
January 2011 in “Analytical Letters” This study demonstrated that a flow injection method using potassium permanganate for detecting minoxidil provided accurate recoveries and agreed closely with HPLC results, showing potential for effective analysis of commercial samples.
2 citations
,
January 2023 In a mouse model, this study found that nano-sized molybdenum accelerated hair growth and reduced oxidative stress markers, with enhancements observed when combined with minoxidil. It suggests potential for this combination as a novel topical treatment for hair loss, pending further clinical validation.
September 2013 in “Science” This study found that single-crystal magnesium samples smaller than 100 nm exhibited increased plastic deformation due to greater activation of nonbasal planes as local flow stresses approached 2 GPa.
January 2019 in “Florida International University Digital Commons (Florida International University)” This research describes using advanced mass spectrometry imaging techniques to analyze gunshot residue and map molecular components in biological samples, such as tumors and mosquito ovarian follicles, at unprecedented spatial resolution and specificity.
6 citations
,
August 2014 in “Spectroscopy Letters” This study reported that the calculated and experimental electronic and vibrational properties of minoxidil were in good agreement, providing detailed insights into its molecular structure and thermal behaviors.
3 citations
,
December 2022 in “Russian Journal of General Chemistry” In this experiment, CoCr2O4 spinel chromite nanocatalysts showed high catalytic efficiency with a 95.6% yield in producing 4-substituted diaminopyrimidine oxides from 2,6-diamino-4-chloropyrimidine N-oxide, while maintaining stable performance over five reuse cycles.
January 2014 in “대한미용학회지” In this study, the researchers found that micronizing hinokitiol using supercritical carbon dioxide impacted its particle size, with increased temperature enlarging particles and increased pressure reducing them.
research News
February 2023 in “Chemistry & Industry” 9 citations
,
August 2024 in “Journal of Orthopaedic Translation” This study suggests that bioactive ceramics could be an effective universal strategy for treating musculoskeletal disorders by targeting the Piezo1-modulated intracellular calcium pathway during bone and muscle formation.
March 2024 in “Organic letters” This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.
5 citations
,
January 2004 in “Analytical Sciences X-ray Structure Analysis Online” This structural study reports on the crystal properties of a compound used for treating alopecia, revealing different conformations and nitrogen hybridization in its piperidine rings.
75 citations
,
March 2007 in “Journal of Biological Chemistry” This review discusses the complexities and uncertainties in the pathways and mechanisms for disulfide bond formation in multicellular organisms and reports no new experimental findings.
45 citations
,
February 2011 in “IOP Conference Series Materials Science and Engineering” This study developed a sensor that effectively measures Tl+ cation in solutions with a wide dynamic range and low detection limit, responding linearly within the concentration range 1.0 × 10−8 to 1.0 × 10−1M.
70 citations
,
February 2009 in “Biological Trace Element Research” June 2015 in “Reactions weekly”