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research Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata
This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.
research COMPARATIVE STUDY OF TWO CONCENTRATIONS (2.5MG/ML AND 5 MG/ML) OF INTRALESIONAL TRIAMCINOLONE ACETONIDE IN THE TREATMENT OF ALOPECIA AREATA
This study found that both 2.5 mg/mL and 5 mg/mL concentrations of intralesional triamcinolone acetonide are effective for treating patchy alopecia areata, but the higher concentration promoted greater hair regrowth and density with more side effects.
research Advances in polymeric nano-delivery systems targeting hair follicles for the treatment of acne
This review discusses how polymer-based nanocarriers can enhance drug delivery targeting hair follicles for acne treatment, focusing on factors affecting this delivery method, combination technologies to improve follicle targeting, and recent advancements in polymer nanodrug-delivery systems.
research Synthesis and Performance of Potassium Monoester Maleate: A Multifunctional Surfactant Towards Hair Repair
In this study, researchers synthesized new surfactants with hair repair properties, finding that they effectively restored the hydrophobic barrier of damaged hair and improved combing ease compared to untreated hair, highlighting their potential in haircare products.
research Effect of a non-ionic surfactant on skin-retention of cationic minoxidil microparticles suspended in an anionic surfactant solution
This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.
research Cutaneous Corticosteroid Injection and Amaurosis
This report discusses historical cases of visual side effects from scalp corticosteroid injections for alopecia areata and attributes their rarity now to improved injection techniques and smaller particulate sizes in suspensions.
research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair-Follicle Neogenesis
This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.
research Treatment of acne keloidalis nuchae and dissecting cellulitis of the scalp with diclofenac sodium gel: a case series
This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
research Effect of injectable calcium alginate-amelogenin hydrogel on macrophage polarization and promotion of jaw bone osteogenesis
This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.
research Direct access to novel chromeno-pyrimidine-N-oxides via tandem base catalyzed double nucleophilic addition/dehydration reaction
This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.
research Latanoprost Loaded in Polymeric Nanocapsules for Effective Topical Treatment of Alopecia
research Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers
This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.
research All-in-one polysaccharide hydrogel with resistant vascular burst pressure and cooperative wound microenvironment regulation for fatal arterial hemorrhage and diabetic wound healing
This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
research Protective effect of conditioning agents on Afro‐ethnic hair chemically treated with thioglycolate‐based straightening emulsion
This study found that adding certain conditioning agents, including jojoba oil and lauryl PEG/PPG‐18/18 methicone, to ammonium thioglycolate straightening emulsions protected Afro-ethnic hair from protein loss and improved resistance to breakage.
research A Randomized, Multicenter, Evaluator-blind Study to Evaluate the Safety and Effectiveness of VYC-12L Treatment for Skin Quality Improvements
VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.
research Occlusion and hydration of scars: moisturizers versus silicone gels
In this study, researchers found that moisturizers like Alhydran and DermaCress provided superior hydration and occlusion compared to silicone gel, suggesting these moisturizers may be a patient-friendly and cost-effective alternative for scar management.
research [Studies on monilethrix].
This report describes four cases of monilethrix in children and concludes that periodic inhibition of keratin synthesis, not a metabolic defect, may explain the hair abnormality.
research [Electrophoretic studies of acid mucopolysaccharides in skin, prekeratin of hair follicles and in keratoses of wool].
This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.
research [Clinical effect of flucort ointment on eczema].
This abstract explores the roles of dermal fibroblasts and keratinocytes in hair follicle neogenesis and regeneration but does not present new experimental results; it suggests more study is needed on the dermal sheath.
research Development and Characterization of Hydrogel containing Finasteride
In this study, the researchers developed a cellulose-based hydrogel that provides sustained drug release with improved bioavailability and stability over time.
research Experimental and Finite Element Analysis of a Residual Hair Keratin‐based Hydrogel with Calcium for Atorvastatin Sequestration, Release, and In Vitro Activity
In this study, keratin‐based hydrogels incorporating calcium ions were developed to effectively deliver atorvastatin, showing potential for localized anti‐fibrotic therapy through controlled drug release and maintaining drug bioactivity in vitro, supported by thorough physicochemical and mechanical characterization.
research TOPICAL IMMUNOTHERAPY IN DERMATOLOGY
This review discusses the use of topical immunotherapy for severe alopecia areata and resistant viral warts, highlighting diphencyprone's advantages and the need for careful handling to avoid staff sensitisation; it reports no new clinical results.
research Injectable self-healing ceria-based nanocomposite hydrogel with ROS-scavenging activity for skin wound repair
This study found that an injectable ceria-based nanocomposite hydrogel improved wound healing and epithelium regeneration, including hair follicle and adipocyte tissue formation, in full-thickness skin wound models.
research Using polyquaternium-64 to condition damaged hair
Polyquaternium-64 helps damaged hair look healthy again.
research Hollow-adjustable polymer microneedles for prolonged hypoglycemic effect on diabetic rats
research Synergistic effect of carbodiimide and dehydrothermal crosslinking on acellular dermal matrix
This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.
research Application of exopolysaccharides in cosmetics
This study discusses the potential of microbial exopolysaccharides as safer cosmetic ingredients compared to synthetic chemicals like parabens and BHA, which may cause skin damage and cancer; exopolysaccharides offer benefits like antimicrobial and antioxidative effects without harmful impacts.
research Improved Humidity-Resistant Hair Straightening Using a Cysteamine-Derived Amino Acid Compound
In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
research Analysis of keratin films as screening tools for predicting the efficacy of potential hair dyes
This research found that translucent keratin films absorbed more dye than opaque films, suggesting they may serve as better screening substrates for evaluating hair dye effectiveness.