Analysis of Keratin Films as Screening Tools for Predicting the Efficacy of Potential Hair Dyes

    June 2019 in “ Coloration Technology
    Tova N. Williams, Harold S. Freeman
    Studysummary This research found that translucent keratin films absorbed more dye than opaque films, suggesting they may serve as better screening substrates for evaluating hair dye effectiveness.
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    The study explored the use of keratin films as a screening tool for predicting the efficacy of potential hair dyes. CI Acid Orange 7 dye was applied to both opaque and translucent keratin films. Time-of-flight secondary ion mass spectrometry images showed uniform dye penetration in both film types. However, ultraviolet-visible analysis indicated that the translucent film had a higher dye concentration. Scanning electron microscopy suggested that the higher porosity of the opaque film led to more dye desorption during rinsing. Thus, the translucent film was deemed a better substrate for screening new hair dyes.
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