research Pill Organizers and Cutters: Risks and Restrictions on Use
Pill organizers and cutters can help with taking medication regularly but may affect the medication's effectiveness and safety.
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research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Finasteride Use During Pregnancy and Early Neonatal Outcome: A Case Report
Baby born healthy despite mom taking finasteride, but more research needed.
research Role of Plasminogen Activator Inhibitor Type 1 (PAI-1) in PCOS Patients
People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
research Hair Loss After Terbinafine Treatment
Terbinafine can cause hair loss.
research Androgenetic Alopecia: Overview
AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
research Cytokines
Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.
research Hormonal and Clinical Evaluation of Patients with Moderate Body Hair Growth
Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.
research The Relationship Between ABO And Rh Blood Groups With Alopecia Areata
AB+ blood group is more common in alopecia areata patients.
research Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Scalp Hair Sweating as a Predictor of Hair Cortisol Level in Humans Compared to Obesity and Other Confounders
Scalp hair sweating is a significant predictor of hair cortisol levels.
research Association Between Stress and Bilateral Symmetrical Alopecia in Free-Ranging Formosan Macaques in Mt. Longevity, Taiwan
Stress is likely causing hair loss in Formosan macaques.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
research Matrix Matching in Quantitative Bioanalysis by LC-MS/MS: A Dream or a Reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Selections from Current Literature: Androgenetic Alopecia - The Science Behind a New Oral Treatment
New oral treatment, finasteride, effectively and safely treats common hair loss.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research Antiandrogen Therapy in Hidradenitis Suppurativa: Finasteride for Females
Finasteride helps reduce hidradenitis suppurativa symptoms in females.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk
Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
research Hair Pathology
Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.
research Illness and Femininity in Hilary Mantel’s Giving Up the Ghost
The document concludes that Hilary Mantel's memoir shows how childhood experiences affect adult health, criticizing modern medicine for ignoring the mental aspects of physical illness.
research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research Abstracts
Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.
research Topically Applied Minoxidil in Baldness
Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Oral cyclosporin doesn't stop hair loss.
research Understanding Hair Loss
Finasteride improves hair growth and satisfaction in men with male pattern baldness but may cause sexual side effects.
research Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells
Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.