research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
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research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization
The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
research Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process
New compounds were found to help increase hair growth and decrease hair loss.
research Improvement of Androgenetic Alopecia with Topical Sophora Flavescens Aiton Extract, and Identification of the Two Active Compounds in the Extract That Stimulate Proliferation of Human Hair Keratinocytes
Sophora flavescens extract helps hair growth and treats hair loss.
research Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway
Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research Effect of Miscanthus Sinensis Var. Purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice
Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
research Clinical, Pathological, and Molecular Features of Classical and L-Type Atypical BSE in Goats
Both classical and L-type atypical BSE from cattle can infect goats with different incubation times, and tests can distinguish between the two strains.
research A Fast and Efficient UPLC-ESI-MS/MS Method for Detection, Identification, and Quantitative Analysis of Bioactive Substances in Medicinal Herbal Extracts for Preventing Hair Loss
Researchers developed a quick and sensitive method to identify and measure hair growth-promoting substances in a herbal mix.
research Clinical, Trichoscopic, and Folliscopic Identification of the Impact of Metabolic Syndrome on the Response to Intradermal Dutasteride 0.02% Injection in Patients with Female Pattern Hair Loss: A Prospective Cohort Study
Metabolic syndrome reduces effectiveness of hair loss treatment.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities
The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
research Challenges Associated With the Identification of Germline Variants on Myeloid Malignancy Genomic Profiling—A Singaporean Experience
Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
research Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle
BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
research Identification of Llama KRTAP7-1 and KRTAP8-1 Fiber Genes and Polymorphism Screening
Mutations in specific llama genes may affect fiber quality for textiles.
research Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking
Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.
research Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits
N6-methyladenosine affects hair follicle development differently in Rex and Hycole rabbits.
research The Identification of Bipotent Dermal Stem Cells and the Role of Anti-Inflammatory Macrophages During Hair Follicle Regeneration
research Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes
Ectodysplasin inhibits Wnt signaling to help form hair follicles.
research Feline Lymphangiosarcoma – Definitive Identification Using a Lymphatic Vascular Marker
Lymphangiosarcoma was confirmed in cats with specific skin symptoms using a lymphatic marker.
research Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat
The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.
research Identification of the C-Terminal Tail Domain of AHF/Trichohyalin as the Critical Site for Modulation of the Keratin Filamentous Meshwork in the Keratinocyte
The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.
research Molecular Basis of Androgenetic Alopecia
research Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA
Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
research Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Merremia Peltata as a Potential Anti-Alopecia Treatment
The compound 16 from the Merremia peltata plant could potentially be a good treatment for hair loss (alopecia) due to its strong activity and favorable skin absorption.
research Developmental Plasticity of Patterned and Regenerating Oral Organs
Fish teeth and taste bud densities are linked and can change between types due to shared genetic and molecular factors.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis
The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.