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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

A genetic mutation in the LIPH gene causes hair loss and growth defects.

Proteins with added sugars are crucial for plant root hair growth.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Dutasteride is more efficient than finasteride, but individual results vary.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

The new minoxidil and salicylic acid hydrogel improves alopecia treatment.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Fatty acid transport protein 4 is essential for skin and hair development.

Keratin peptides can change hair shape gently without harsh chemicals.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Finasteride may affect PNMT, causing side effects.

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.

Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.

Undergraduate research experiences boost students' research skills, confidence, and career aspirations.

Special astroglia cells improved stroke recovery in rats, a hair growth drug reduced cancer spread, and tiny magnesium structures were more easily shaped.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

New sensor detects minoxidil accurately and effectively.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.