9 citations
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March 2016 in “Natural Product Research” This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.
April 2016 in “Journal of Investigative Dermatology” This study found that in mutant NRAS melanoma, MEK inhibitors led to increased AKT signaling and reduced MIG6, a change that may enhance cell migration and invasiveness.
13 citations
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July 2019 in “Chemical papers/Chemické zvesti” This study developed and optimized a molecularly imprinted polymer-based electrochemical sensor, demonstrating its ability to detect minoxidil with high sensitivity and selectivity at concentrations as low as 0.3 nM, and successfully applied it for minoxidil measurement in various real sample matrices.
4 citations
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February 2012 in “Chinese Science Bulletin” In this study, overexpression of the MtAnn3 gene in Medicago truncatula roots was associated with altered root hair growth polarity in a calcium-free environment.
14 citations
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November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
34 citations
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October 2021 in “Scientific Reports” This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.
10 citations
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December 2023 in “International Journal of Nanomedicine” This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.
June 2024 in “European Journal of Pharmaceutics and Biopharmaceutics” This study reported that using photoacoustic waves to enhance transdermal delivery of encapsulated minoxidil can significantly increase hair growth while reducing treatment frequency and systemic side effects.
January 2026 in “Dermatologic Therapy” This review indicates that while microneedling shows potential for managing androgenetic alopecia, particularly in combination with other treatments, the existing evidence is of low to moderate quality, and more robust trials are needed to confirm its clinical efficacy and safety.
December 2025 in “Saudi Pharmaceutical Journal” This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.
15 citations
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May 2009 in “Chemical Physics Letters” This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.
3 citations
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October 2022 in “Nano Letters” This study found that a microneedle patch using manganese thiophosphite showed greater hair regrowth potential compared to minoxidil, even with less frequent application, for treating androgenetic alopecia.
February 2023 in “International Journal of Pharmaceutics” In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.
14 citations
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March 2022 in “Macromolecular Rapid Communications” This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.
August 2019 in “Stem cells” This paper reviews the role of miRNAs in stem cell therapies and hair follicle growth, reporting no new findings but highlighting recent insights into fertility treatment and wound healing.
March 2014 in “Journal of The American Academy of Dermatology” Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.
113 citations
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November 2017 in “Scientific Reports” This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.
5 citations
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January 2019 in “Methods in molecular biology” In this study, researchers showed that multiphoton microscopy with fluorescent protein tagging enables single-cell imaging and tracking in live transgenic mice, offering new insights into cell dynamics in stem cell research compared to traditional histological methods.
January 2023 in “Nanomedicine & nanotechnology open access” This review suggests that microneedling shows promise for improving hair quality, thickness, and density in treating androgenetic alopecia, but standardized treatment protocols are currently lacking.
128 citations
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July 2009 in “International Journal of Pharmaceutics” This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.
June 2022 in “International journal of drug delivery technology” This study investigated the hair growth-promoting effect of topical nebivolol cream in mice, but the abstract does not provide specific results or conclusions.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.
June 2022 in “Annals of Indian Academy of Neurology” This case report describes a rare association where herpes zoster infection may have triggered the first attack of NMOSD with systemic vasculitis in a patient, suggesting potential overlaps in immunopathogenesis.
January 2026 in “New Journal of Chemistry” This study synthesized calcium citrate nanoparticles to improve the solubility and reduce the irritation of minoxidil solutions for treating androgenetic alopecia.
March 2014 in “Journal of The American Academy of Dermatology” Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.
11 citations
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March 2023 in “Marine Drugs” In this study, researchers isolated five new compounds from Monascus purpureus wmd2424 and found that four exhibited mild antifungal activity against several fungi.
March 2025 in “Molecular Neurobiology” July 2025 in “Journal of Drug Delivery Science and Technology” Hydrogel microneedles with special nanoparticles and growth factor improve hair growth better than minoxidil for hair loss treatment.
133 citations
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May 2016 in “Cell Host & Microbe” In this study, human dermal fibroblasts were identified as natural host cells that support productive Merkel cell polyomavirus infection, and the MEK antagonist trametinib was introduced as an effective inhibitor to control the virus.