Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.

This double-blinded randomized clinical trial found that combining topical vitamin D analog (calcipotriol) and intra-lesion PRP led to a greater reduction in hair loss severity in alopecia areata patients compared to either treatment alone, with significant improvements observed across all groups.

This study observed that successful weight loss following bariatric surgery may improve some skin conditions and metabolic profiles, but also may lead to a decrease in vitamin B12 levels, suggesting a need for nutritional supplements.

This review explores the efficacy and safety of treatments for dissecting cellulitis of the scalp, revealing a predominance of case reports and series, and concludes that randomized controlled trials are needed for better evidence-based therapies.

This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

The authors concluded that the dermal response to epidermal Wnt/β-catenin signaling depends on distinct fibroblast lineages, with each responding to different paracrine signals such as Hedgehog and TGF-β.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This review examines beta-catenin's role in stem cell renewal, lineage selection, and tumor formation in the epidermis and reports no new experimental findings.

This study found that Brg1, a chromatin-remodeling enzyme, plays a critical role in hair regeneration and early epidermal repair by regulating bulge stem cells through a Brg1-Shh interaction.

This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.

This study found that linseed oil, rich in flavonoids and terpenoids, significantly improved burn wound healing in terms of faster contraction, reduced inflammation, and enhanced tissue regeneration compared to other treatments, without adverse effects.

This study found poor agreement among dermatopathologists in identifying and grading fibrosis in traction alopecia, suggesting the need for better diagnostic methods for early fibrosis detection.

This study found that women with AIDS had significantly reduced epithelial thickness and more telogen hair follicles on the scalp compared to women without AIDS.

This study found no strong genetic link between hair color and alopecia areata risk, although a weak inverse association with blond hair was suggested, noting the results are exploratory and require further investigation with larger cohorts.

In this study, researchers developed an acellular bioscaffold made from ovine tendon collagen with an antibacterial coating for treating skin wounds. They found that genipin crosslinking improves the scaffold's properties, and with plasma polymerisation, it enhances antibacterial activity, potentially benefiting wound healing.

This study found that dysregulation of systemic Th1, Th2, and Th17 cytokines is associated with alopecia areata, with specific cytokines linked to disease activity and treatment response.

This study found that alopecia areata patients in Central Europe with comorbid chronic inflammatory disorders, especially atopic dermatitis, bronchial asthma, or Hashimoto's thyroiditis, had an increased likelihood of experiencing early-onset, severe, or prolonged disease compared to those without such comorbidities.

This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.

This review examines complex regional pain syndrome (CRPS I) mechanisms, including immune dysregulation and psychological factors, but reports no new clinical results; the authors highlight potential diagnostic refinements.

This review discusses the challenges in diagnosing primary cicatricial alopecias and explores how improved communication and digital pathology could enhance diagnosis, but it reports no new clinical results.

This review summarizes recent findings on the combined use of chitosan and melatonin, highlighting their synergistic effects in wound healing, anti-cancer therapies, and tissue engineering, with further potential applications in cosmetology, aesthetic medicine, and veterinary practice.

This study found that ATR-FTIR spectroscopy combined with machine learning effectively differentiated alopecia areata patients from healthy controls with an AUC of 0.85, and also showed promise in predicting treatment response, particularly through alterations in the Amide I band.

This review highlights the lack of a comprehensive synthesis of stem cell therapy research by categorizing current studies according to medical specialty and stem cell type, while analyzing their advantages and limitations across various medical disciplines.

This narrative review discusses the promising role of photobiomodulation in dermatology, emphasizing its non-invasive nature and potential benefits, but acknowledges the need for further research to establish standard protocols.

In this study, researchers observed that heat stress significantly affected hair and skin traits in two indigenous goat breeds, with Kodi Aadu goats demonstrating greater thermal resilience compared to Kanni Aadu goats, potentially due to differences in gene expression and methylation.

In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.

This review summarized advancements in intestinal lymphatic drug delivery, emphasizing the evolving understanding of lymphatics as active players in health and disease, which has led to innovative therapeutic strategies and enhanced pharmacokinetic outcomes via this delivery route.

This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.

This study found that ethosomes containing 30% ethanol slightly improved the targeting of dutasteride to hair follicles in vitro, with a higher targeting factor compared to dried ethosomes and controls after 24 hours on porcine skin.