Treatments for Dissecting Cellulitis of the Scalp: A Systematic Review and Treatment Algorithm

Dissecting cellulitis of the scalp (DCS) is a chronic inflammatory condition that leads to abscesses, nodules, fistulas, and scarring alopecia, making it difficult to manage. This systematic review aimed to evaluate the efficacy and safety of DCS treatments by analyzing 110 relevant articles involving 417 patients. Most studies were case reports or series, with treatment options including systemic antibiotics, oral retinoids, biologics, procedural treatments, combination agents, and topical treatments. Oral retinoids and photodynamic therapy were the most studied interventions. The review highlights the need for randomized controlled trials to establish a robust, evidence-based treatment approach for DCS.