Evaluation of the Effect of Topical Calcipotriol Versus Platelet-Rich Plasma Versus a Combination of Both on Patients with Alopecia Areata

    November 2023 in “ Research Square (Research Square) ”
    Mahmoud Ali, Moustafa A. El Taieb, Ali Mohamed Younis Younis … Eisa M. Hegazy

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This double-blinded randomized clinical trial found that combining topical vitamin D analog (calcipotriol) and intra-lesion PRP led to a greater reduction in hair loss severity in alopecia areata patients compared to either treatment alone, with significant improvements observed across all groups.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 17

    1. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    2. Evaluation of Platelet-Rich Plasma on Hair Regrowth and Lesional T-Cell Cytokine Expression in Alopecia Areata: A Randomized Observer-Blinded, Placebo-Controlled, Split-Head Pilot Study Journal of The American Academy of Dermatology · 2020
    3. Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study Dermatology and therapy · 2020
    4. Evaluation of Platelet-Rich Plasma vs Intralesional Steroid in Treatment of Alopecia Areata Journal of Cosmetic Dermatology · 2019
    5. Topical Calcipotriol Versus Oral Vitamin D in the Treatment of Alopecia Areata Fayoum University Medical Journal/Fayoum University Medical Journal · 2019
    6. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    7. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    8. Efficacy and Safety of Topical Calcipotriol in Management of Alopecia Areata: A Pilot Study Dermatologic Therapy · 2017
    9. Trichoscopy as a Useful Method to Differentiate Tinea Capitis from Alopecia Areata in Children at Zagazig University Hospitals International Journal of Dermatology · 2016
    10. The Role of Lymphocytes in the Development and Treatment of Alopecia Areata Expert Review of Clinical Immunology · 2015
    11. Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study PubMed · 2015
    12. Intralesional Platelet-Rich Plasma vs. Intralesional Triamcinolone in the Treatment of Alopecia Areata: A Comparative Study International journal of medical research and health sciences · 2015
    13. Trichoscopic Findings in Alopecia Areata and Their Relation to Disease Activity, Severity, and Clinical Subtype in Turkish Patients Australasian Journal of Dermatology · 2013
    14. Successful Treatment of Alopecia Areata with Topical Calcipotriol Annals of dermatology/Annals of Dermatology · 2012
    15. Clinical Evaluation of Alopecias Using a Handheld Dermatoscope Journal of The American Academy of Dermatology · 2011
    16. Clinical Significance of Dermoscopy in Alopecia Areata: Analysis of 300 Cases International Journal of Dermatology · 2008
    17. Guidelines for the Management of Alopecia Areata British Journal of Dermatology · 2003

    Related research 1

    1. Platelet-Rich Plasma (PRP) as a New Approach and Promising Therapy in Patients With Alopecia Areata Medica Hospitalia: Journal of Clinical Medicine · 2023