Evaluation of the Effect of Topical Calcipotriol Versus Platelet-Rich Plasma Versus a Combination of Both on Patients with Alopecia Areata

In a double-blinded randomized clinical trial involving 39 patients with Alopecia Areata, the effects of topical calcipotriol, intra-lesion PRP, and their combination were compared. Group I received calcipotriol, Group II received PRP, and Group III received both treatments. All groups showed significant reductions in SALT scores and dermoscopic findings, with the combination treatment (Group III) showing the most substantial improvement, followed by PRP alone (Group II), and then calcipotriol alone (Group I). The study concluded that combining calcipotriol and PRP is particularly effective in reducing symptoms of Alopecia Areata.