1 citations
,
October 2022 in “Journal of Cosmetic Dermatology” In this study, combining 2% minoxidil with weekly microneedling significantly improved hair regrowth in women with female pattern hair loss compared to using minoxidil alone, with an 85% effective rate reported in the group receiving both treatments over a 24-week period.
May 2024 in “Journal of biomaterials science. Polymer ed.” This study found that three-layer dissolving microneedles for delivering Minoxidil showed improved skin drug penetration and reduced irritation risk compared to traditional Minoxidil cream, suggesting a promising alternative for alopecia areata treatment.
1 citations
,
January 1992 in “Juntendō Igaku/Juntendo igaku” This review discusses the hair growth mechanisms of minoxidil, suggesting both increased blood flow and a direct effect on hair follicles, but reports no new clinical results.
6 citations
,
February 2018 in “PubMed” This study suggests that minoxidil may promote hair growth in androgenetic alopecia by increasing intracellular calcium, which enhances stem cell differentiation, offering insights for new drug development.
November 2024 in “Journal of Drugs in Dermatology” This article highlights the need for a comprehensive review of injectable minoxidil for hair loss, as existing treatments primarily focus on topical and oral forms of the medication.
In this study, a case was reported where oral Minoxidil led to severe ocular complications, specifically Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion, resulting in sudden vision loss which improved upon discontinuation.
1 citations
,
December 2022 in “̒Ulūm-i dārūyī” This study found that in a rat model, minoxidil promoted better wound healing through potential anagen hair growth effects, while dexamethasone suppressed wound healing by reducing collagen production.
1 citations
,
May 1992 in “Pharmacological Research”
July 2012 in “Reactions Weekly” Minoxidil use was linked to a rare eye condition that improved after stopping the treatment.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that minoxidil sulfate enhanced hair growth in CRF-OE mice, with increased hair growth scores observed at 2 and 4 weeks after treatment.
July 2025 in “Journal of Investigative Dermatology” Low-dose oral minoxidil is safe for the heart in the short term for hair loss patients.
April 2023 in “Klinicheskaya dermatologiya i venerologiya” This study highlights that while oral Minoxidil at doses ineffective for hypertension may promote hair regrowth, uncertainties remain about its long-term outcomes and effects in patients with underlying conditions.
22 citations
,
May 2003 in “Planta Medica” This study found that torilin from Torilis japonica fruit extract inhibited 5 alpha-reductase in vitro more effectively than alpha-linolenic acid but less effectively than finasteride.
July 1994 in “Annals of Pharmacotherapy” Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
18 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” In isolated rat lymph vessels, this study found that ATP-sensitive potassium channel openers impair lymph contractions and reduce lymph flow, potentially contributing to peripheral edema.
January 2024 in “Wiadomości Lekarskie” This presentation reviews the potential of novel device-based interventions for heart failure treatment, noting that despite advances in drug therapy, many patients still experience significant symptoms. Results of these interventions, which address limitations of medication, are not reported in this abstract.
73 citations
,
September 2016 in “Journal of Translational Medicine” This review discusses the drug repurposing of cardiovascular medications like aspirin and statins for new uses, including potential anti-tumor effects, noting promising experimental outcomes but less conclusive clinical trials, particularly in the field of cancer treatment.
1 citations
,
February 2020 in “Drug Design Development and Therapy” Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.
October 2025 in “American Journal of Clinical Dermatology” Low-dose oral minoxidil can effectively promote hair growth but requires careful monitoring for safety.
November 2024 in “Cureus” In this case report, a 24-year-old male experienced severe vasoplegic shock after ingesting a large amount of minoxidil solution, requiring an unprecedented 180 hours of norepinephrine support for blood pressure maintenance, highlighting the need for extensive supportive care following minoxidil intoxication.
21 citations
,
September 2001 in “Graefes Archive for Clinical and Experimental Ophthalmology” This study found that minoxidil inhibited lens epithelial cell migration, proliferation, and collagen secretion in vitro, suggesting it may help prevent postoperative capsular opacification.
25 citations
,
June 2018 in “Clinical and Experimental Dermatology” This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.
74 citations
,
July 1991 in “The Journal of Urology” This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.
January 2026 in “American Journal of Translational Research” In this study, the combination of metoprolol and spironolactone in patients with coronary heart disease and heart failure significantly improved cardiac function and reduced inflammation and oxidative stress markers compared to spironolactone alone, with better clinical efficacy and fewer adverse effects.
August 2025 in “Journal of Cosmetic Dermatology” In this study, Gupta et al. observed that pericardial effusions were dose-independently associated with oral minoxidil use for hypertension but not frequently reported during its use for alopecia, suggesting a potential underreporting issue and the need for standardized risk monitoring in alopecia treatment.
26 citations
,
August 2018 in “Dermatologic Therapy” This review discusses the research supporting the approval and use of minoxidil for androgenic alopecia and reports no new clinical results, emphasizing recent findings and developments.
March 2023 in “Clinical Toxicology” This correspondence highlights a case of intradermal minoxidil injection in a patient but does not report new research findings.
May 2025 in “Modern technologies in ophtalmology” This research found that long-term use of minoxidil may rarely be associated with side effects unrelated to its known mechanism, though such effects are not well understood.
October 2019 in “UNESP Institutional Repository (São Paulo State University)” This study found that oral minoxidil 1 mg daily was as effective and safe as topical minoxidil 5% solution for treating female pattern hair loss over 24 weeks, but more likely to cause excessive hair growth elsewhere.
3 citations
,
May 2022 in “Journal of The American Academy of Dermatology” This source notes that while low-dose oral minoxidil is effective for treating androgenetic alopecia, it has been associated with electrocardiogram changes and palpitations even at low doses.