Minoxidil: Topical or Oral

April 2023 in “ Klinicheskaya dermatologiya i venerologiya ”

Ammar Helalinasab, Mohammad Bahadoram, Esma'il Akade, G. Houshmand

minoxidil topical minoxidil oral minoxidil androgenetic alopecia female pattern hair loss hair follicles Rogaine

TLDR Oral Minoxidil may be better for hair growth than topical, but its long-term safety is unclear.

Minoxidil, initially used for hypertension, is now FDA-approved for topical use in treating androgenetic alopecia and female pattern hair loss due to its effects on hair follicles. Recent studies suggest that oral Minoxidil, at doses ineffective for hypertension, can promote hair growth without the side effects associated with its systemic use. While oral Minoxidil appears more favorable than topical application, the long-term effects and safety for patients with underlying conditions remain uncertain.

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Research cited in this study

9 / 9 results

research Efficacy and Safety of Oral Minoxidil in Female Androgenetic Alopecia

14 citations , September 2020 in “Dermatologic Therapy”

Oral minoxidil improves hair density in women with androgenetic alopecia, with mild side effects.

research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety

59 citations , July 2020 in “Journal of The American Academy of Dermatology”

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

research Minoxidil And Its Use In Hair Disorders: A Review

117 citations , August 2019 in “Drug Design Development and Therapy”

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

research Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia

52 citations , May 2019 in “Journal of The American Academy of Dermatology”

Low-dose oral minoxidil effectively improves male hair loss with mild side effects.

research Case Series of Oral Minoxidil for Androgenetic and Traction Alopecia: Tolerability and the Five C’s of Oral Therapy

36 citations , September 2018 in “Dermatologic Therapy”

Oral minoxidil helps hair growth, is cost-effective, and mostly well-tolerated.

research Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells

42 citations , February 2018 in “International Journal of Molecular Sciences”

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

research Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension

74 citations , May 2004 in “Journal of Clinical Hypertension”

Minoxidil effectively treats severe hypertension, but watch for side effects.

research Minoxidil: Mechanisms of Action on Hair Growth

397 citations , February 2004 in “British Journal of Dermatology”

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use

96 citations , October 1981 in “Drugs”

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

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6 / 1000+ results

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 11 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 3 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 2022 Official beginner guide for "I'm losing my hair, what can I do?"

in STARTER GUIDE 686 upvotes 3 years ago

Hair loss treatments include Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. Additional options are Dutasteride, oral Minoxidil, and hair transplants.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 415 upvotes 7 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 2 years ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

Related Research

4 / 4 results

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations , January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

July 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil can effectively treat patchy hair loss by stimulating hair growth.

research Topical minoxidil in the treatment of alopecia areata

April 1985 in “Plastic & Reconstructive Surgery”

A study conducted in 1985 with 30 patients evaluated the effects of 1% topical minoxidil on alopecia areata and alopecia totalis. The results showed a significant incidence of hair regrowth, with 16 patients achieving a cosmetically acceptable response. No side effects were reported. The study concluded that while topical minoxidil could induce new hair growth in cases of alopecia areata, it was less effective for more severe forms like alopecia universalis and totalis. Despite this, minoxidil was considered relatively non-toxic, easy to use, and free of systemic or local side effects compared to other treatments.

research Alopecia Areata Treated With Topical Minoxidil

16 citations , April 1984 in “Archives of Dermatology”

Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.