1 citations
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April 2021 in “Aesthetic Cosmetology and Medicine” This article reviews various applications and substances in mesotherapy for skin conditions and discusses the benefits of series treatments, reporting no new clinical results.
2 citations
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November 2018 in “Cell Stem Cell” This study reported that wound-resident mesenchymal cells can be reprogrammed to generate epithelial tissues, aiding in the closure of large, non-healing ulcers without signs of malignant transformation.
56 citations
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November 2022 in “Biomolecules” This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.
2 citations
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July 2017 in “IEEE Photonics Journal” This study found that combining second-harmonic generation with optical coherence tomography may effectively evaluate wound healing by monitoring collagen formation and optical signal changes in regenerated tissue.
41 citations
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September 2012 in “Cellular and Molecular Life Sciences” This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.
August 2026 in “Pharmaceutics” In this study, radiofrequency microporation significantly improved topical minoxidil delivery and hair regrowth in a mouse model of androgenetic alopecia, with minimal systemic exposure compared to oral administration, suggesting it could be a promising needle-free option for topical therapy.
131 citations
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May 2015 in “Experimental Dermatology” This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.
2 citations
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December 2022 in “Bio-Design and Manufacturing” This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.
57 citations
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October 1996 in “Dermatologic clinics” This study found that using hyaluronic acid microneedles to deliver minoxidil significantly reduced hair loss in chemotherapy-induced alopecia mice, with only 10% of the dose used in topical applications.
3 citations
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March 1994 in “The Journal of Dermatologic Surgery and Oncology” This article reports that the use of an ultrasharp tungsten electrode was deemed a useful tool in hundreds of scalp reduction procedures for hair restoration at Peterson Medical Institute.
58 citations
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June 2006 in “Plastic and Reconstructive Surgery” This study successfully developed a reproducible mouse model demonstrating fetal scarless wound healing, which may provide insights for minimizing scarring in adults.
January 2026 in “Nanoscale Advances” This review provides an overview of microneedle-assisted photomedicine, detailing diagnostic and therapeutic strategies, design principles, and challenges for translating this approach to skin disease management.
August 2024 in “Nature Communications” This study found that in female mice, softer, lightly crosslinked gelatin-based hydrogels promoted better wound healing with less scarring and inflammation compared to stiffer, heavily crosslinked hydrogels, affecting immune and stromal cell behavior.
908 citations
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July 2015 in “British Journal of Dermatology” This article reviews the cellular and molecular processes of acute and chronic wound healing, emphasizing the need for collaboration between researchers and clinicians to advance therapeutic solutions; it presents no new clinical results.
6 citations
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August 2020 in “Journal of Plastic Reconstructive & Aesthetic Surgery” This paper suggests various cost-effective home practice models for maintaining and developing microsurgical skills during COVID-19 restrictions, offering alternatives that minimize reliance on clinical settings.
October 2025 in “Burns & Trauma” This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
9 citations
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January 1998 in “Studia Anglica Posnaniensia: international review of English Studies” This review discusses the cellular and molecular basis of wound-induced hair neogenesis and its age-related changes, reporting no new clinical results but highlighting areas for future research.
This systematic review examined the potential of microneedling for anterior neck scars but found no eligible studies directly investigating this application. Indirect evidence from other body regions suggests possible benefits, underscoring the need for targeted research to validate these findings for neck surgery patients.
8 citations
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January 2012 in “Dermatology Research and Practice” This article describes a new subcision technique intended to simplify the procedure for surgeons without reporting clinical results or outcomes.
June 2026 in “Precision medicine and engineering.” In this study, researchers created a hydrogel that reduces oxidative stress and releases a pro-angiogenic drug in response to enzyme activity, which accelerated healing and improved tissue regeneration in chronic diabetic wounds during in vivo experiments.
106 citations
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January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.
May 2023 in “Current Medicinal Chemistry” This review highlights the potential of microneedle devices in dermatology for conditions like skin aging and autoimmune skin diseases, emphasizing their ability to facilitate targeted drug delivery by creating temporary skin pathways.
September 2024 in “Journal of the American Academy of Dermatology” This study evaluated microneedling's effect on hair loss, finding a minor reduction in SALT scores for androgenetic alopecia patients, but no significant change for fibrosing or alopecia areata groups. Further skin biopsy analyses are pending to explore other changes beyond SALT scores.
August 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that combining microneedling at depths of 0.5 mm or 1 mm with minoxidil tincture significantly improved hair density and diameter in men with androgenetic alopecia compared to minoxidil alone, although the deeper microneedling also led to higher adverse reactions.
July 2021 in “Plastic and reconstructive surgery. Global open” This study found that treating wounds in mice with the drug verteporfin, which inhibits mechanical signaling, leads to skin regeneration associated with the activation of Wnt pathway proteins.
March 2025 in “Advanced Materials” This study developed a novel hydrogel dressing, QL@MAB, which facilitates accelerated healing of infected diabetic wounds in rats by offering prolonged drug release, water retention, and adaptive drug delivery in response to high glucose levels in the wound environment.
4 citations
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October 2022 in “Cell Reports Physical Science” This study developed a novel mineralization strategy using metal-polyphenol coordination for dynamic control of nano-scale processes, enhancing hydrogels that support wound healing with antibacterial and angiogenesis-promoting properties.
21 citations
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November 2020 in “Chemical Engineering Journal” In this study, an injectable hydrogel incorporating antibacterial agents was shown to effectively heal wounds and promote hair follicle and capillary regeneration, offering a promising approach for skin tissue engineering.
This article discusses a novel device for applying mediums to human and animal tissues and reports no new clinical results, focusing on its potential for precise applications and enhanced cell transplants.
6 citations
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November 2008 in “Hair transplant forum international” This article reviews the development of trichophytic closure techniques in hair restoration surgery aimed at reducing donor site scarring, but it does not report new clinical outcomes.