Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement

    May 2023 in “ Current Medicinal Chemistry
    Gislaine Ricci Leonardi, Mariane Massufero Vergilio, James C. Birchall, Lonetá Lauro Lima, Rodrigo Alvarenga Rezende
    Image of study
    TLDR Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
    Microneedle (MN) devices, recognized as a top emerging technology, offer a minimally invasive method to bypass skin barriers, facilitating drug delivery for dermatological and cosmetic purposes. This review highlights the potential clinical benefits of MNs in treating autoimmune-mediated inflammatory skin diseases, skin aging, hyperpigmentation, and skin tumors by creating transient pathways for therapeutic materials. The literature supports the efficacy of MN patches in enhancing drug delivery to deeper skin layers, underscoring the importance for healthcare professionals to adopt these systems as they become clinically available.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 791 results

      community My personal experience/observations fighting AGA seriously for 5 years

      in Treatment  43 upvotes 2 weeks ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community Six months of only Dermarolling

      in Progress Pictures  157 upvotes 1 year ago
      User tried dermarolling for hair loss and shared progress pictures. Some suggest adding finasteride and minoxidil, while others debate effectiveness and frequency of dermarolling.

      community Comprehensive Microneedling Guide

      in Microneedling  290 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Dermaroller vs dermastamp vs dermapen

      in Microneedling  5 upvotes 1 month ago
      Microneedling is debated for hair loss treatment, with some users finding it beneficial for minoxidil absorption and others skeptical of its effectiveness. Alternatives like finasteride and minoxidil are recommended, while tools like dermarollers, dermapens, and dermastamps are discussed for their pros and cons.

    Similar Research

    5 / 570 results