Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement

    May 2023 in “ Current Medicinal Chemistry ”
    Gislaine Ricci Leonardi, Mariane Massufero Vergilio, James C. Birchall, Lonetá Lauro Lima, Rodrigo Alvarenga Rezende
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    TLDR Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
    Microneedle (MN) devices, recognized as a top emerging technology, offer a minimally invasive method to bypass skin barriers, facilitating drug delivery for dermatological and cosmetic purposes. This review highlights the potential clinical benefits of MNs in treating autoimmune-mediated inflammatory skin diseases, skin aging, hyperpigmentation, and skin tumors by creating transient pathways for therapeutic materials. The literature supports the efficacy of MN patches in enhancing drug delivery to deeper skin layers, underscoring the importance for healthcare professionals to adopt these systems as they become clinically available.
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