August 2000 in “Microscopy and Microanalysis” This study used novel methods to detect and map iodine concentrations in pig skin, finding iodine present in the coating, stratum corneum, and tissue around hair follicles.
50 citations
,
March 1992 in “PubMed” This review discusses the clinical manifestations of malnutrition in children, particularly highlighting the overlapping skin changes from various nutrient deficiencies, and reports no new clinical results.
April 2026 in “ACS Applied Materials & Interfaces” In this study, researchers developed a probiotic-based microneedle system combining Weissella cibaria and clascoterone to target androgenetic alopecia, which in a mouse model improved hair density, vascular regeneration, and reduced inflammation, suggesting a promising treatment approach.
27 citations
,
March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
January 2025 in “Open Science Framework” The project aims to validate a nutritional intervention targeting the Redox–NO–Androgen Axis to restore mitochondrial, endothelial, and hormonal balance in male health disorders related to oxidative stress.
April 2025 in “Cancer Research” This study examined older adults undergoing chemotherapy and found that nutritional-inflammatory biomarker ratios were significantly linked to cognitive impairments, treatment side effects, and quality of life indicators, suggesting these lab measurements might help identify high-risk individuals for intervention.
January 2019 in “Trace Elements in Medicine (Moscow)” Hair analysis may help monitor health in children with Down syndrome and obesity.
6 citations
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May 2022 in “Pharmaceutics” This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.
January 2011 in “Journal of Jiangnan University” This study developed a validated method for analyzing minoxidil in hair care cosmetics, demonstrating good precision and recovery rates.
18 citations
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January 1978 in “Advances in experimental medicine and biology” This study found that hair samples from children with kwashiorkor or marasmic kwashiorkor had about 20% less cystine compared to one child with adequate protein nutrition, suggesting the need for further research.
1 citations
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June 2025 in “Environmental Research” In this study, researchers reported that adult females approaching menopause in Canada generally had similar or lower blood concentrations of toxic, essential, and trace elements compared to their peers, but most participants showed zinc levels below the proposed adequacy threshold.
126 citations
,
November 1987 in “The Journal of Pediatrics” This study reports that selenium deficiency in children on long-term total parenteral nutrition may lead to symptoms like erythrocyte macrocytosis and skin and hair depigmentation, which improved with selenium supplementation.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that all five toxic microelements analyzed were most prevalent in the Caspian thin-fingered gecko's bone and muscle tissues, suggesting their tolerance to these elements in polluted areas.
9 citations
,
January 2003 in “Organic Eprints (International Centre for Research in Organic Food Systems, and Research Institute of Organic Agriculture)” This research observed that while organic farming systems in Southern Norway showed decreased phosphorus over time and variable nitrogen retention, the mulching of plant material could enhance vegetable yields, suggesting a need for innovative nutrient management strategies in organic farming.
5 citations
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August 2020 in “Advances in Hematology” In this study, an intervention to automatically measure ferritin detected iron deficiency in about 28% of women with alopecia, potentially helping to address hair loss.
24 citations
,
February 2016 in “Journal of Animal Physiology and Animal Nutrition” The researchers reported that the net mineral requirements for weight gain in Morada Nova lambs differ from commonly recommended values by the Agricultural and Food Research Council.
17 citations
,
October 1981 in “American Journal of Clinical Nutrition” This study found that individuals with protein-calorie malnutrition, especially those with kwashiorkor, required significantly less force to pluck hair compared to well-nourished patients.
20 citations
,
May 2023 in “Biological Trace Element Research” This study found that repeated oral intake of 0.5 or 5 mg/kg of cobalt ferrite nanoparticles induced pulmonary toxicity in rats, with dose-dependent oxidative stress and inflammation observed, but no notable toxicity was seen at a 0.05 mg/kg dose.
4 citations
,
January 1993 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study developed a highly sensitive fluorescent assay for measuring enzyme activity in single hair follicles, allowing the efficient analysis of over 100 samples per day.
7 citations
,
May 2007 in “Nutrition Journal” This study found that due to variability in measurements, hair pluckability is not a reliable indicator of adult nutritional status, although it may hold potential in certain emergency situations if improved for consistency.
3 citations
,
January 2009 in “Eclética Química” This study proposed a simple, rapid permanganometric method for determining minoxidil concentrations in pharmaceutical samples, offering comparable accuracy to chromatographic methods with recovery rates of 94.5 to 95.2%.
May 2025 in “VETERINARY SCIENCE TECHNOLOGIES OF ANIMAL HUSBANDRY AND NATURE MANAGEMENT” In this study, researchers determined that poor feed quality and nutritional deficiency, especially low vitamin A levels, were leading causes of impaired reproductive function in nutria, with deficiencies most pronounced during February-March and linked to clinical signs like growth retardation and alopecia.
6 citations
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November 1988 in “Journal of the American Academy of Dermatology” The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
July 2018 in “Current Analytical Chemistry” This study observed that carbon paste electrodes catalyze the electrooxidation of minoxidil more efficiently than other electrode types, with a detection limit of approximately 20 ng mL^-1.
November 2024 in “Advances in Pharmacology and Pharmacy” This study validated a UV-spectrophotometric method for accurately detecting Minoxidil and Tofacitinib citrate concentrations in bulk and gel formulations for alopecia areata, showing high recovery rates and indicating the method's suitability for routine analysis.
September 2021 in “Crop research/Crop Research” This study reported that a biotin-rich nutrition bar stored in aluminum foil packaging showed reduced bacterial growth and remained edible for 30 days compared to other packaging materials.
4 citations
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June 1980 in “American Journal of Clinical Nutrition” Malnutrition can change hair color due to altered copper and zinc levels.
September 2012 in “British Small Animal Veterinary Association eBooks” This review examines nutrient-responsive dermatoses in companion animals and reports no new results, highlighting that improved diet quality can enhance skin and hair coat health.
109 citations
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January 1980 in “Science of the total environment” This paper reviews chemical analysis methods for trace elements in human hair and supports a no-wash policy due to challenges in distinguishing between endogenous and exogenous element sources.
July 2023 in “Biomolecules” This study established a novel in vivo "whisker follicle microinjection assay" using mouse whiskers to evaluate hair growth and pigmentation effects of various chemicals and proteins, identifying minoxidil, ruxolitinib, and RSPO1 as growth promoters, while deoxyarbutin inhibited pigmentation and Nbl1 emerged as a growth inhibitor.