Micro-Segmental Hair Analysis: Detailed Procedures and Applications in Forensic Toxicology

The document reviewed the micro-segmental hair analysis (MSA) technique, developed in 2016, which involves cutting a single hair strand at 0.4-mm intervals to correspond with daily hair growth. This method provided detailed drug distribution profiles in hair, aiding in forensic toxicology by offering evidence of drug use and insights into drug uptake mechanisms. The review included experiences from the authors' research group and highlighted the method's applications, such as estimating drug consumption days and time of death. It also summarized procedures for laboratory use, discussed current limitations, and suggested future research directions.