This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.
April 2025 in “International Journal of Pharmaceutics” Liposomes improve minoxidil delivery to hair follicles, enhancing treatment for hair loss.
1 citations
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June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
June 2022 in “Scientific Reports” This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.
11 citations
,
May 1957 in “Journal of the American Medical Association” This review clarifies what constitutes an emollient and explains that both cosmetic and pharmaceutical emollients share the same functions, reporting no new research findings.
1 citations
,
June 2025 in “Therapeutic Delivery” This article reviews microneedle technology as a transdermal drug delivery platform without presenting new clinical results, emphasizing its engineered microstructure arrays for enhanced penetration.
January 2026 in “Lithuanian University of Health Sciences” This study reported that gels containing methyl cellulose exhibited the highest consistency factor and optimal homogeneity compared to those made with hydroxypropyl cellulose or its combination with pullulan, indicating the significant impact of gelling agents on gel properties.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
October 2025 in “Coloration Technology” In this study, a new delipidisation method that removes over 97% of key lipids from wool rapidly and without yellowing was reported to improve wool processing and printing quality.
47 citations
,
January 2003 in “Pharmaceutical Research”
November 2025 in “Saudi Journal of Medical and Pharmaceutical Sciences” In this study, researchers developed and tested hair gels using pectin from mango and coconut oil as a potential natural treatment for traction alopecia in black women, reporting stability in some formulations and rheological properties that may support their use in innovative phytocosmetics.
25 citations
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May 2008 in “Journal of cosmetic dermatology” This study found that adding certain conditioning agents, including jojoba oil and lauryl PEG/PPG‐18/18 methicone, to ammonium thioglycolate straightening emulsions protected Afro-ethnic hair from protein loss and improved resistance to breakage.
1 citations
,
June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
9 citations
,
June 2021 in “International Journal of Pharmaceutics” This study found that polymeric micelle nanocarriers delivered pharmacologically relevant amounts of spironolactone to the epidermis and upper dermis, with higher delivery to pilosebaceous units, suggesting potential for treating glucocorticoid-induced impaired wound healing and pilosebaceous androgen-related skin diseases.
24 citations
,
April 2011 in “Journal of Chemical & Engineering Data” This study measured the solubility of minoxidil in various solvents, finding the highest solubility in methanol and lowest in water, with solubility correlating to temperature.
March 2012 in “Korean Journal of Microscopy” This study found that nanoparticles can penetrate the skin, but artifacts produced during specimen preparation complicate accurate observation, and proposed a method for reducing errors in imaging quantum dots as tracers.
December 2009 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that iontophoresis significantly increased the retention of minoxidil sulfate in hair follicles, potentially improving drug delivery for androgenic alopecia treatment.
3 citations
,
April 2011 in “Expert Review of Dermatology” This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.
March 2026 in “Journal of Nanobiotechnology” This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.
85 citations
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January 2007 in “Journal of Drug Targeting” This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.
18 citations
,
October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics” In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.
September 2020 in “Farmacja Polska” This review discusses various applications of foam systems in drug form technology, highlighting their potential to enhance drug solubility and release modifications, but reports no new clinical results.
14 citations
,
February 2024 in “Pharmaceutics” This review highlights that while nanoparticle-loaded dissolving microneedles have considerable promise for enhancing transdermal drug delivery, progress is delayed by insufficient understanding of their in vivo behavior, which the authors emphasize as crucial for advancing clinical applications.
13 citations
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February 2018 in “Bio-medical Materials and Engineering” This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This report describes the successful resolution of an epidermoid cyst using a minimally invasive approach with intralesional injection of recombinant enzymes.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
1 citations
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August 2019 in “IntechOpen eBooks” This article discusses the use of mesotherapy in dentistry and reports no new clinical results, emphasizing the need for further research on its applications for oral problems.
33 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.
34 citations
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March 2004 in “Journal of Liposome Research” This study found that neutral liposomes were most effective at delivering minoxidil into pilosebaceous units compared to other tested formulations.
December 2023 in “Journal of molecular structure” This study found that hair membrane fluidity is low in the cuticle but high in the cortex and medulla, with treatments like ionic surfactants and oleic acid increasing fluidity in hydrated hair; however, dehydration significantly reduces fluidity throughout the hair.