4 citations
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January 2019 in “Egyptian Journal of Dermatology and Venereology” This study suggests that androgenetic alopecia moderately affects quality of life, with women experiencing a higher impact and showing a greater willingness to pay for treatment than men.
September 2024 in “Revista Brasileira de Cirurgia Plástica” This study reported that a frontoplasty endoscopic subperiosteal technique using three small incisions was effective and aesthetically beneficial in treating upper facial aging among patients with frontotemporal alopecia, though it did result in some minor complications such as eyebrow correction issues and recurring glabellar wrinkles.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this preprint, an integrative regenerative protocol involving microneedling, plant-derived exosomes, and other therapies was used to treat androgenetic alopecia in an elderly woman, resulting in improved hair density and scalp coverage.
July 2025 in “Anais Brasileiros de Dermatologia” The Brazilian version of the Alopecia Areata Quality of Life Index is reliable for assessing patients' quality of life.
October 2019 in “Our Dermatology Online” In this study, researchers reported that androgenetic alopecia is associated with significantly decreased quality of life, particularly impacting younger patients and those with severe or long-standing hair loss.
January 2021 in “Menoufia Medical Journal (Print)” This study reported that androgenetic alopecia affects the psychosocial aspects and quality of life differently depending on marital status and occupational category, with married patients and professional workers experiencing higher emotional impact.
June 2026 in “Mendeley Data” This dataset provides supplemental material for a study on long-term particulate matter exposure and androgenetic alopecia risk, including additional exposure data and sensitivity analyses, but reports no new clinical results.
August 2024 in “International Journal of Molecular Sciences” The study investigated immune cell patterns around the hair follicle infundibulum in androgenetic alopecia, revealing significant differences in immune signatures between patients with AGA and control donors, specifically noting an enrichment of CD4 cells in the patient group.
July 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” In this study, researchers identified the miR-22-3p/CLIC4 signaling pathway as a key regulator in hair follicle miniaturization among androgenetic alopecia models, suggesting that targeting CLIC4-mediated sonic hedgehog pathway disruption may offer new therapeutic strategies for AGA treatment.
January 2018 in “Surgical and Cosmetic Dermatology” In this study, researchers validated a software-based method that quantitatively assesses the effectiveness of treatments for hair loss by calculating the area of hair loss using contrast in standardized photographs, proving effective for both early and advanced cases of androgenetic alopecia and telogen effluvium.
6 citations
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January 2013 in “Case reports in endocrinology” This article reviews acromegaloid facial appearance syndrome and presents a case in a 57-year-old woman, emphasizing the need for more cases to understand its clinical features and inheritance patterns.
May 2015 in “Hair transplant forum international” This review discusses androgenetic alopecia and reports no clinical findings; the authors highlight a need for further research.
February 2023 in “Journal of The American Academy of Dermatology” This study found that transgender and gender diverse patients on masculinizing hormone therapy had 2.5 times the rate of androgenetic alopecia compared to cisgender women.
February 2025 in “European Journal of Dermatology” This review explored the complex mechanisms behind androgenetic alopecia, highlighting genetic influences and factors like increased 5-α reductase and androgen receptors in hair follicles, while identifying microinflammation and oxidative stress as related issues.
192 citations
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June 1992 in “Journal of The American Academy of Dermatology” Hair loss can cause low self-esteem, anxiety, and depression in men.
March 2026 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This systematic literature review found that exosome and PRP therapies show promise as effective, minimally invasive options for treating androgenetic alopecia, with clinical benefits potentially superior to or complementary to minoxidil, although standardization and larger clinical trials are needed to confirm long-term safety and efficacy.
September 2026 in “Endocrine and Metabolic Science” This study found that while androgenetic alopecia was common and more frequent with age and in men within the PERSIAN Guilan Cohort, it was not independently associated with depression.
4 citations
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September 2020 in “Frontiers in Microbiology” In this study, algal oligosaccharides effectively countered key factors in androgenetic alopecia pathogenesis, improving hair growth indicators in vitro and in mice.
This article discusses the organizational aspects of the II National Academic Congress of Dermatology in Brazil and reports no new research findings.
This study found that both oral minoxidil and finasteride altered prostate tissue in mice, with more severe changes seen in finasteride-treated groups, suggesting greater implications for male reproductive health compared to minoxidil.
180 citations
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September 1999 in “British Journal of Dermatology” This review discusses the psychological and social impacts of androgenetic alopecia and suggests that medical treatments can have some positive psychological effects, highlighting the condition's moderate stress and impact on body image.
July 2026 in “Frontiers in Cellular and Infection Microbiology” This study found that patients with androgenetic alopecia had increased scalp microbial diversity and reduced Staphylococcus abundance, particularly in the frontal and vertex regions, suggesting this dysbiosis as a sensitive indicator of AGA.
March 2026 in “Current Topics in Medicinal Chemistry” This review found that gut microbiota and exosomal microRNAs may collectively impact androgenetic alopecia progression by modulating immune responses and intercellular communication, suggesting new therapeutic possibilities; however, further research is needed to clarify these mechanisms.
March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
1 citations
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May 2023 in “Revista Eletrônica Acervo Saúde” In this study, researchers reported that individuals with post-COVID-19 alopecia experienced a significant impact on their quality of life, particularly in the vitality domain, when compared to those without alopecia.
June 2026 in “Drug Delivery and Translational Research” This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.
July 2018 in “Benha Journal of Applied Sciences” In this study, researchers found that patients with alopecia areata had significantly higher levels of miR-203 in their skin compared to healthy controls.
1 citations
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May 2022 in “Revista Contemporânea” This systematic review analyzed treatments for androgenetic alopecia, finding that combining two therapies, such as oral minoxidil with another treatment, resulted in better outcomes than using monotherapies alone, though some patients experienced non-severe side effects.
35 citations
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March 2014 in “British Journal of Dermatology” This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative review explores molecular signaling pathways and their impact on hair follicle microenvironments in androgenetic alopecia, alongside potential treatments like stromal vascular fraction therapies and exosome-based strategies.