Study of Skin Expression of MicroRNA-146a in Patients with Alopecia Areata

July 2018 in “ Benha Journal of Applied Sciences ”

A.M. El-Refaie, N.E. Sorour, A.I. Mustafa, O.S. El-Shimi, Samah Mohammed

microRNA-146a microRNA-203 miR-203 alopecia areata non-scarring hair loss RT-qPCR pathogenesis AA

TLDR Higher levels of miR-203 may contribute to hair loss in alopecia areata.

The study investigated the role of microRNA-203 (miR-203) in patients with alopecia areata (AA), a non-scarring hair loss condition. It included 30 AA patients and 20 healthy controls. Skin biopsies were analyzed using RT-qPCR to measure miR-203 expression. Results showed a significantly higher level of miR-203 in AA patients compared to the control group, suggesting a potential role of miR-203 in the pathogenesis of AA.

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