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This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.

In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.

This study found that using 1,4-butylenediamine bismaleimide for hair perming through thiol-Michael click chemistry offers comparable efficiency to conventional oxidative methods, with enhanced durability and reduced damage to hair fibres, preserving mechanical, color, and surface properties.

This study found that acetyl zingerone methyl ether (MAZ) in hair dyes and haircare products may reduce oxidative damage, improve hair condition, and enhance the longevity and quality of dyed hair color.

This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.

In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.

This study suggests that a hair lotion containing methyl myristate loaded in cationic niosomes may effectively accelerate pigmentation in aged C57BL/6 mice compared to free methyl myristate.

In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.

This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.

In this study, carboxymethylalanyl disulfide keratin was shown to effectively prevent hair damage during repeated bleaching and permanent waving treatments.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.

This study found that povidone iodine, thiabendazole ointment, captan ointment, and Burroughs Wellcome Ringworm Ointment were effective against Trichophyton equinum var. autotrophicum in horses, but large-scale use may be limited by practicality and cost.

This study developed a novel antidandruff shampoo with ketoconazole-coated zinc oxide nanoparticles that showed enhanced antifungal activity against Malassezia furfur compared to standard ketoconazole treatments, suggesting it could be a more effective alternative for dandruff management.

This study found that chemically modifying hair with 2-iminothiorane hydrochloride improved the permanence of hair setting without damaging the hair by increasing disulfide bonds.

Minoxidil topical foam is a better, less irritating treatment for hair loss.

This study found that "clean" shampoos are less likely to contain allergenic preservatives compared to traditional shampoos, but both types use fragrance equally, which can be irritating or allergenic.

This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.

This study concluded that clotrimazole, miconazole, and tolnaftate appeared safe in guinea pigs, whereas gentian violet showed potential for severe ototoxicity, and nystatin left a concerning residue.

This study found that a single application of 0.1% aqueous benzalkonium chloride solution effectively treated dermatomycosis caused by Trichophyton species in guinea pigs.

This study reviewed existing literature and reported that 1% Zinc pyrithione in anti-dandruff shampoo effectively inhibits the growth of fungi responsible for dandruff, aligning with the regulatory limits set by Indonesian health authorities.

This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.

This study found that subcutaneous injections of certain chelators led to skin and hair depigmentation, increased skin elasticity, and disturbed hair growth in minks, without affecting fur quality.

In this study, the researchers formulated an herbal shampoo and found it exhibited excellent cleansing properties and foam stability, comparable to commercial shampoos, suggesting it as a safe and cost-effective alternative to marketed formulations.

In this study, a new delipidisation method that removes over 97% of key lipids from wool rapidly and without yellowing was reported to improve wool processing and printing quality.

This study found that ozonated olive oil exhibited antifungal activity against Trichophyton mentagrophytes, comparable to the standard antifungal terbinafine, in an in vivo rat study, suggesting it may serve as an alternative treatment for dermatophytosis.

This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.