Acetyl Zingerone Methyl Ether Protects Hair Against Oxidative Damage From Permanent Dyes and Extends Hair Color Longevity

August 2024 in “ International Journal of Cosmetic Science ”

Ratan K. Chaudhuri, Thomas A. Meyer, Rachel Blinder, Martin Swanson Vethamuthu, Valérie George, Adebayo A. Adeniyi, Neha Manhas, Parvesh Singh

acetyl zingerone methyl ether MAZ permanent hair dyes oxidative damage antioxidant properties hydroxyl radicals singlet oxygen α-tocopherol hair gloss color quality haircare ingredient hair dyes antioxidants vitamin E shampoo conditioner

Studysummary This study found that acetyl zingerone methyl ether (MAZ) in hair dyes and haircare products may reduce oxidative damage, improve hair condition, and enhance the longevity and quality of dyed hair color. Our plain-language summary of this paper — not a Tressless recommendation.

Acetyl zingerone methyl ether (MAZ) has been identified as an effective haircare ingredient that protects hair from oxidative damage caused by permanent hair dyes and environmental stressors like sun exposure. In a 28-day clinical study, MAZ demonstrated superior antioxidant properties, reducing hydroxyl radicals and singlet oxygen more efficiently than α-tocopherol. When incorporated into hair dyes, MAZ did not interfere with color development or grey coverage and improved hair condition immediately after dyeing. Additionally, using MAZ-infused shampoo and conditioner over a 28-day period significantly preserved hair gloss and color quality, maintaining a fresh appearance compared to controls. This research supports MAZ as a valuable addition to haircare products for enhancing color longevity and overall hair health.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

9 / 9 results

research Mechanisms of Impairment in Hair and Scalp Induced by Hair Dyeing and Perming and Potential Interventions

1 citations , May 2023 in “Frontiers in medicine”

This review explores how hair dyes and perms can damage hair structure and notes that while some adverse outcomes like skin irritation and allergic reactions have been reported, evidence from human studies remains inconsistent regarding potential risks, including cancer.

research The Chemistry Mechanism of Hair Dyes

1 citations , December 2022 in “Middle East Journal of Science”

This review covers hair dye formulations, their mechanisms, and potential applications, but reports no new findings; the authors highlight the process of oxidative dyeing and repairing damaged hair.

research Structural Investigation on Damaged Hair Keratin Treated with α,β-Unsaturated Michael Acceptors Used as Repairing Agents

5 citations , December 2020 in “International journal of biological macromolecules”

This study found that shikimic acid- and maleate-based hair repair agents modified the structure of hair fibers, though they did not increase disulfide bridge content in the hair cortex.

research Spectroscopy as a Tool to Evaluate Hair Damage and Protection

2 citations , November 2018 in “International Journal of Cosmetic Science”

This study proposes a simple fluorescence method to evaluate hair damage and protection, suggesting that emissive properties of hair can aid in substantiating cosmetic claims.

research Mechanism of Cuticle Hole Development in Human Hair Due to UV Radiation Exposure

8 citations , March 2018 in “Cosmetics”

In this study, researchers found that UV radiation causes hydroxy radicals to form cuticle holes specifically between the cuticle layers in wet hair, unlike random holes caused by Fenton's reaction.

research Oxidative Modification in Human Hair: The Effect of the Levels of Cu (II) Ions, UV Exposure and Hair Pigmentation

16 citations , October 2015 in “Photochemistry and photobiology”

This study found that higher concentrations of copper (II) ions in human hair increase protein oxidative modification, contributing to hair damage regardless of UV exposure and pigmentation level.

research Copper and Calcium Uptake in Colored Hair

13 citations , March 2010 in “International Journal of Cosmetic Science”

This study used nanoscale secondary ion mass spectrometry to locate where calcium and copper are concentrated in colored hair, finding these metals particularly in the cuticle's sulfur-rich regions.

research About Photo-Damage of Human Hair

66 citations , September 2005 in “Photochemical & photobiological sciences”

This review discusses the current understanding of hair photodamage and photodegradation and reports no new findings; it highlights unresolved questions about radiation effects and melanin's role in different hair types.

research An Ultrastructural Study of Hair Fiber Damage and Restoration Following Treatment with Permanent Hair Dye

40 citations , February 2002 in “International Journal of Dermatology”

In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.