Mechanism of Cuticle Hole Development in Human Hair Due to UV Radiation Exposure

The study concluded that UV radiation caused significant damage to human hair by creating cuticle holes and peeling off cuticle layers. This damage was attributed to the oxidation of linoleic acid, a polyunsaturated fatty acid present between the cuticle layers, leading to the production of highly reactive hydroxy radicals. These radicals were responsible for forming cuticle holes and overall hair damage. The findings emphasized the importance of protecting hair from UV exposure to maintain its structural integrity and appearance.