Efficacy of Ozonated Olive Oil as a Topical Treatment for Dermatophytosis Caused by T. Mentagrophytes in Rat Model
January 2025
in “
Letters in Drug Design & Discovery
”
Studysummary This study found that ozonated olive oil exhibited antifungal activity against Trichophyton mentagrophytes, comparable to the standard antifungal terbinafine, in an in vivo rat study, suggesting it may serve as an alternative treatment for dermatophytosis. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the antifungal effects of ozonated olive oil as a topical treatment for dermatophytosis caused by Trichophyton mentagrophytes in a rat model. Thirty male Wistar albino rats were treated with different concentrations of ozonated olive oil and compared to terbinafine. Results showed that ozonated olive oil had a minimum inhibitory concentration (MIC) of 2.5 μg/mL, demonstrating significant antifungal effects by reducing inflammation and promoting hair growth, similar to the effects of terbinafine. The study concludes that ozonated olive oil may be a viable alternative treatment for Trichophyton infections.
