4 citations
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December 2023 in “Advanced science” This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.
23 citations
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July 2020 in “Aging Cell” In this study, researchers found that glycan profiles in epidermal stem cells differed between young and old mice, suggesting these changes may serve as molecular markers for aging.
69 citations
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December 2015 in “BMC plant biology” This study provides evidence that five Hyp-O-GALT genes are crucial for AGP galactosylation and that AGP glycans are vital for various aspects of plant growth and development.
9 citations
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April 2019 in “International journal of molecular sciences” In this study, growing human hair follicles in a defined glycosaminoglycan hydrogel ex vivo promoted cell survival, proliferation, and activation of hair growth-related signaling pathways, suggesting GAG-based hydrogels could modulate the hair follicle growth cycle.
March 2024 in “International journal of molecular sciences” This study found that human meibomian glands differ significantly from free and hair-associated sebaceous glands in morphology and lipid composition, making them highly specialized holocrine glands.
1 citations
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July 2025 in “Advanced Materials” This study reports on a zinc-coordinated tri-enzyme nanogel system (Zn@nGSC) that mimics natural enzymatic processes to enhance enzymatic activity and cascade efficiency, showing potential in wound healing, hyperglycemia treatment, and antibacterial effects in a murine model of post-pancreatectomy.
44 citations
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July 1993 in “Journal of Investigative Dermatology” August 2026 in “Materials Technology” This study developed a multifunctional TA-MoS2-SF hydrogel for diabetic ulcer treatment, demonstrating enhanced photothermal bactericidal effects, immune environment remodeling, and fibroblast proliferation, suggesting it may serve as an effective 'antibacterial-immunomodulatory-repair' strategy.
8 citations
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January 2023 in “International journal of molecular sciences” This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.
In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.
September 2016 in “Toxicology letters” The researchers reported that hydrogels made from methacrylated glycol chitosan and hyaluronic acid with chondroitin sulfate may be suitable for load bearing soft tissue repair, showing enhanced chondrocyte viability and metabolic activity.
3 citations
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March 2022 in “Polymers” This study found that applying glycosaminoglycans fractions from ascidian tunics stimulated human follicle dermal papilla cell proliferation and, when used on mice hair for 28 days, produced a hair growth effect comparable to Minoxidil.
1 citations
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May 2025 in “European Polymer Journal” This study developed a multifunctional dressing with the MeGel-SFSR composition, which showed faster healing and better tissue regeneration in diabetic wounds compared to controls, by utilizing a herbal compound and enhanced mechanical support, promoting hair follicle regeneration, collagen deposition, reduced inflammation, and vascularization in vivo.
October 2022 in “ACS Applied Materials & Interfaces” This study reports that the newly developed SA-Ca(II) hydrogel has tunable mechanical properties, high biocompatibility, and potential applications in wearable protections and stimuli-responsive electronics.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that TGM2 appears to play a crucial role in sebocyte differentiation and may act as a negative regulator of lipid metabolism in sebaceous glands.
February 2026 in “ACS Omega” This study developed a multifunctional hydrogel, QTMP-Gel, which significantly accelerated wound healing in an oral mucositis hamster model by providing antioxidant and antibacterial effects, reducing inflammation, and controlling infection.
11 citations
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July 2024 in “Biomimetics” This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.
April 2020 in “Rice Research Repository (Rice University)” This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.
16 citations
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September 2006 in “The Journal of Immunology” This study identified that mouse MILL1 and MILL2 are glycoproteins distinct from human MICA/B, primarily due to their association with β2-microglobulin and TAP-independent surface expression.
8 citations
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March 2024 in “Regenerative Therapy” This study found that using uniform poly(lactic-co-glycolic) acid microspheres to deliver insulin-like growth factor 1 stabilizes the protein and enhances its sustained delivery, supporting stem cell functions comparably to traditional methods, and showing potential for tissue and organ regeneration.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” This study found that a unique transglutaminase in guinea pig hair-follicles, distinct from liver transglutaminase, likely plays a role in forming protein cross-links via ε(γ-glutamyl)lysine bonds.
November 2025 in “Journal of Investigative Dermatology” N,N-Dimethylglycine sodium salt may improve skin health and treat hair loss.
July 2026 in “Materials Today Bio” This study developed a novel hydrogel that improved healing in diabetic infected wounds on mobile sites by controlling infection, inflammation, and mechanical stress, promoting skin regeneration without excess scarring.
April 2026 in “Microsystems & Nanoengineering” This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.
4 citations
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May 1981 in “Australian Journal of Biological Sciences” This study observed that rat dermal tissue cultures, rich in hair follicle cells, produce various glycosaminoglycans, including hyaluronic acid and dermatan sulfate, which change in synthesis and sulfation patterns over time.
March 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.
1 citations
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January 1984 41 citations
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February 2005 in “Experimental Cell Research” This study suggests that the MAEG protein may facilitate epithelial–mesenchymal interactions during hair follicle development by binding to RGD-binding integrins like α8β1.
December 2023 in “Frontiers in microbiology” This study reported that mannan oligosaccharides improved the fur quality, immune response, antioxidant status, and gut microbiota of fur-growing raccoon dogs, suggesting they could potentially replace antibiotics in their diet.
July 2026 in “International Journal of Molecular Sciences” This review highlights how cyclodextrin-polysaccharide hybrids can advance drug delivery and environmental cleanup by improving the solubility and stability of hydrophobic molecules, serving as promising platforms for biomedical applications and efficient sorbents for wastewater treatment.