Production of Glycosaminoglycans by Rat Hair Follicle Cells In Vitro
May 1981
in “
Australian Journal of Biological Sciences
”
New to Hyaluronic Acid? There is a guide in the encyclopedia. Read the guide → Studysummary This study observed that rat dermal tissue cultures, rich in hair follicle cells, produce various glycosaminoglycans, including hyaluronic acid and dermatan sulfate, which change in synthesis and sulfation patterns over time.
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In 1981, a study on rat dermal tissue cultures, which included a significant number of hair follicle cells, demonstrated the production of glycosaminoglycans. These glycans were found both in cell aggregates and in material released from the cells. The study identified several glycosaminoglycan species, including hyaluronic acid, dermatan sulfate, chondroitin-4-sulfate, heparin, and heparan sulfate-C, with hyaluronic acid and dermatan sulfate being secreted into the culture medium. It was observed that the synthesis and sulfation patterns of these glycosaminoglycans changed over time in culture.
