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This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This case report observed significant improvement in hair density and thickness in a male patient with androgenetic alopecia following the addition of mesotherapy, alongside topical minoxidil and oral finasteride, over 20 sessions, with no side effects reported.

This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.

This study suggests that transfection with modified KGF-mRNA enhances keratinocyte reepithelialization in wound therapy by temporarily increasing growth factor expression without affecting nuclear DNA.

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

In this study, the researchers found distinct patterns of TGF-beta 1 and IGF-II expression in pig fetal subcutaneous tissue, suggesting specific regulatory roles in developing adipocytes and muscle tissue.

This study observed abnormal extracellular matrix patterns in hair follicles from alopecia areata patients, particularly in the dermal papilla of large anagen follicles and in catagen follicles from lesional sites.

This review summarizes the mechanisms of mesenchymal stem cell-mediated wound healing and highlights engineering strategies that enhance therapeutic outcomes, but it reports no new clinical results.

In this study, subcutaneous injection of bone marrow mesenchymal stem cells in burned rats significantly improved wound healing by reducing inflammation, scar formation, and wound size, and restoring normal skin structures.

In this study, researchers retrospectively analyzed five children with extensive and refractory alopecia areata treated with mesalazine, observing complete hair regrowth in all patients without side effects, suggesting potential benefits of this treatment combination, though controlled studies are needed for confirmation.

This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.

In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.

This study demonstrated that human dermal mesenchymal stem cells can be differentiated into cardiomyocytes using 5-azacytidine, suggesting potential future applications for treating myocardial infarction.

This review suggests that MSC-derived conditioned media hold promise in dermatology, with studies indicating enhanced therapeutic effects when used alongside treatments like laser therapy and microneedling, leading to improved dermatological outcomes.

This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.

Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.

This review discusses the advances and challenges of using mesenchymal stem cell-derived extracellular vesicles in therapeutic applications and reports no new clinical findings.

This study found that using uniform poly(lactic-co-glycolic) acid microspheres to deliver insulin-like growth factor 1 stabilizes the protein and enhances its sustained delivery, supporting stem cell functions comparably to traditional methods, and showing potential for tissue and organ regeneration.

This study found that intravenous transplantation of human hair follicle-derived mesenchymal stem cells improved trabecular bone mass in osteoporotic mice by enhancing bone formation and reducing bone resorption.

This study concluded that mesotherapy appears effective for treating pattern hair loss, but emphasizes a need for more research comparing it to other treatments due to limited sample sizes.

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.

This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.

This study suggests that hair follicle-derived mesenchymal stem cell transplantation may effectively treat acute pancreatitis by reducing inflammation and promoting pancreatic regeneration in a rat model.

This study found that mesenchymal stem cells derived from dental pulp and adipose tissue have distinct gene expression signatures that suggest potential target diseases for clinical applications.

This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.

This study reports that mesotherapy can lead to serious complications, such as multifocal scalp abscesses and subcutaneous fat necrosis, requiring extensive surgical repair.

In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.

This study found that human hair follicle-derived mesenchymal stem cells effectively maintained human embryonic stem cells in an undifferentiated state, comparable to mouse embryonic fibroblasts under standard conditions.