A Clinical Trial on the Efficacy of Mesotherapy with Dutasteride for Frontal Fibrosing Alopecia

August 2024 in “ JEADV Clinical Practice ”

Patrizia Aguilar-Calderón, Sonia Sofìa Ocampo‐Garza, Maira Elizabeth Herz‐Ruelas, Jorge Ocampo‐Candiani, Adrián Cuéllar‐Barboza, Emmanuel Sánchez‐Meza, Andrea S. Guerra‐Garza, Minerva Gómez‐Flores

mesotherapy dutasteride frontal fibrosing alopecia intralesional injections hair density vellus hair perifollicular erythema scaling pruritus pain FFA

From the encyclopedia

Mesotherapy →

technique to inject very small amounts of beneficial chemicals into the scalp

Dutasteride →

Heavy duty finasteride that comes with higher risks

Studysummary In this clinical trial, 16 women with frontal fibrosing alopecia experienced significant improvements in hair density, vellus hair count, and quality of life after monthly intralesional dutasteride treatments, though larger and longer-term studies are needed to confirm these findings.

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Research cited in this study

3 / 3 results

Guidelines for Clinical Trials of Frontal Fibrosing Alopecia: Consensus Recommendations from the International FFA Cooperative Group

research Guidelines for Clinical Trials of Frontal Fibrosing Alopecia: Consensus Recommendations from the International FFA Cooperative Group

14 citations , June 2021 in “British journal of dermatology/British journal of dermatology, Supplement”

This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.

research Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

56 citations , January 2019 in “Skin appendage disorders”

In this multicenter study, androgenetic alopecia was the most common type of alopecia among both men and women attending specialty hair clinics on four continents.

research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients

339 citations , February 2014 in “Journal of The American Academy of Dermatology”

This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.