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This review found limited support for oral vitamin C and E in treating pigmentary disorders like chloasma, inflammatory conditions, and pressure wounds, with evidence constrained by small, varied studies.

Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.

This study reports a rare case where severe vitamin B12 deficiency was identified as the cause of excessive daytime sleepiness, which resolved after vitamin B12 replenishment.

In this study, alopecia areata and vitiligo patients had significantly lower serum BDNF and vitamin D levels, which were inversely associated with depression and quality of life, suggesting a potential combined role in the development of depression.

This review reports that collagen as a nutraceutical shows promising results for improving skin health in estrogen-deficient women, but more research is needed for scalp hair, nail health, and optimal dosing of curcumin and glutathione.

In this study, silencing P-cadherin in human scalp hair follicles reduced melanogenesis and associated protein expression, suggesting P-cadherin is crucial for normal hair pigmentation via GSK3β-mediated Wnt signaling.

This review discusses recent in vitro and in vivo research suggesting that components of ginseng, such as ginsenosides and gintonin, may have potential skincare benefits, including anti-aging effects and treatment of skin conditions like atopic dermatitis and hypertrophic scars.

This study proposed a model that accurately predicts skin condition using genotype information and machine learning, suggesting potential for creating customized cosmetics.

This case study presents a reversal of hair loss in discoid lupus erythematosus using newer treatments like injectable platelet-rich fibrin.

This review discusses the potential link between low serum vitamin D levels and androgenetic alopecia and reports that vitamin D might be useful for diagnosis and treatment, but no new clinical results are included.

This study concluded that thyroid atrophy, alopecia, and hyperkeratosis in sheep are associated with deficiencies in selenium and zinc in serum and liver.

This scoping review reports that preclinical studies suggest omega fatty acids may promote hair follicle growth, but clinical evidence is mixed, with no support for their standalone use in treating alopecia.

This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.

This review discusses the potential clinical benefits and functional properties of taurine as a conditionally essential amino acid, noting its presence in energy drinks, but reports no new experimental results.

In this study using human cell cultures, type 1 5α-reductase was found to vary in both protein heterogeneity and expression levels across different types of skin cells.

This review explores the potential impact of nutrition on immune-mediated inflammatory skin diseases and evaluates whether dietary changes could help in treatment planning, but it presents no new clinical outcomes.

This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.

In this study, a 6-month randomized controlled trial with postmenopausal women reported that supplementing with soy protein isolate with isoflavones led to significant improvements in skin hydration and reduced wrinkles and facial pigment intensity, but did not affect sebum production.

This case report describes a 17-year-old girl with telogen effluvium and severe hair loss following a suspected COVID-19 infection and a history of similar episodes since childhood.

This review highlights the important role of the vitamin B complex in enhancing tissue repair, reducing inflammation, and improving surgical outcomes in plastic and reconstructive procedures by supporting cellular processes such as mitochondrial efficiency, neurotransmitter biosynthesis, and wound healing pathways.

This study found that incorporating adipose-derived stem cell conditioned medium into a polysaccharide hydrogel effectively reduced scar hyperplasia, with the combination offering better outcomes in preventing hypertrophic scarring compared to the medium alone in a rabbit ear model.

In this review, the authors summarized the potential therapeutic effects of metal ions in treating cardiovascular diseases, highlighting their roles in protecting cells, inducing angiogenesis, and adjusting ion channel functions, as well as discussing delivery strategies involving biomaterials.

This study identified genetic variations associated with black and white wool color in Gangba sheep, enhancing understanding of wool color genetics and aiding selective breeding for specific wool colors in Tibetan sheep.

This review examined the psychological effects, mechanisms, health associations, and treatments related to premature hair graying, highlighting factors like genetics, oxidative stress, smoking, and diet, with the aim of enhancing understanding and addressing its broader implications.

This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.

This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.

This article presents a family case study of dermatopathia pigmentosa reticularis linked to a specific KRT14 gene variant, detailing symptoms and stressing the importance of molecular diagnosis for management.

This study observed that in human scalp hair follicles, BTNL2 expression is lower in stressed conditions, which correlates with increased cytotoxic activity by gamma/delta and CD8+ T cells, suggesting a possible role for BTNL2 in controlling immune responses relevant to alopecia areata.

This case report highlights the significance of alopecia totalis and knuckle pad hyperpigmentation as early indicators of azathioprine-induced myelosuppression and pancytopenia.

This review discusses the off-label uses of retinoids in dermatology, focusing on oral isotretinoin and acitretin, and reports no new clinical results.