Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial

This 24-week randomized double-blind controlled trial involving 44 postmenopausal women found that soy protein isolate with added isoflavones (SPII) significantly improved facial signs of photoaging and skin hydration. The SPII group showed a 7.1% reduction in wrinkle severity and a 2.5% decrease in facial pigment intensity by week 24. Additionally, skin hydration increased by 39% on the left cheek and 68% on the right cheek. No significant changes in sebum production were observed. The study concludes that dietary soy protein supplementation with isoflavones can enhance skin health in postmenopausal women.