This study found that overexpression of antizyme in mice with activated MEK reduced skin tumor growth by inhibiting putrescine accumulation, slowing cell growth, and increasing G2/M transit time.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified that disrupting Mef2c in dermal papilla cells delays the early stages of hair cycle catagen in mice, revealing potential interactions with Sox18 in regulating hair growth.
December 2024 in “Jurnal Syntax Admiration” This study found that MOOEW Hair Tonic had a Return of Investment of over 100%, indicating significant potential for profitable and sustainable business opportunities.
3 citations
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November 2024 in “Pediatric Dermatology” This study found that dermatologic adverse events are common in children taking MEK inhibitors, with selumetinib patients experiencing less severe reactions and a lower risk of dosage adjustments. Age was noted as a factor in the likelihood of specific skin reactions.
This study reported that genome sequencing and analysis of mink hair keratin genes reveal the amino acid composition of key proteins and offer insights into fur biosynthesis, potentially aiding conservation efforts through transgenic animal design to produce mink fur and help save endangered mink species.
April 2016 in “Journal of Investigative Dermatology” This study found that in mutant NRAS melanoma, MEK inhibitors led to increased AKT signaling and reduced MIG6, a change that may enhance cell migration and invasiveness.
January 2023 in “Sovremennye problemy nauki i obrazovaniâ” Miliacin may help prevent hair loss and improve hair growth in mice with a condition similar to human baldness.
January 2024 in “Современные проблемы науки и образования (Modern Problems of Science and Education)” Miliacin helps extend the hair growth phase in mice with hair loss.
January 2019 in “Journal of the American Leather Chemists Association” This study observed that processing techniques such as degreasing, bating, and tanning influence mink skin by altering the distribution of fat glands and collagen fibers, potentially impacting hair follicle structure and mink product quality.
6 citations
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July 2005 in “Farmaco” This study developed a micellar electrokinetic capillary chromatography method for determining minoxidil in Rogaine and generic products, offering a simple and efficient alternative to HPLC.
January 2011 in “Dialnet (Universidad de la Rioja)” This study found that the "After Minoxidil" spray improved hair styling and decreased greasiness after using topical minoxidil, which may enhance compliance and effectiveness.
1 citations
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November 2022 in “Animals” This study found that differences in skin transcriptomes between juvenile and adult mink, as well as between black and white mink, suggest genes regulating hair color are active during early development rather than adulthood.
January 2010 in “Bradford Scholars (University of Bradford)” This study found that microRNAs play key roles in regulating gene expression during the hair cycle in mice, impacting follicle growth and skin homeostasis through mechanisms involving major signalling pathways.
3 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study found that a 12-week supplementation with MePL, a solution of miliacin encapsulated within polar lipids, significantly reduced hair density in the telogen phase and improved scalp dryness and hair brightness in women with telogen effluvium.
12 citations
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July 2011 in “Experimental Dermatology” This study found that mEGF ethosomal delivery systems mainly penetrated mice skin through the pilosebaceous unit and successfully induced hair follicles to transition from the telogen to anagen phase.
149 citations
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June 2010 in “The FASEB journal” In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
5 citations
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February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
March 1996 in “Hair transplant forum international” This article discusses the introduction and market presence of the Italian hair product Kevis but presents no new clinical findings.
1 citations
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April 2012 in “Cancer Research” This study found that overexpression of antizyme in MEK-activated transgenic mice reduced skin tumor development and restored normal differentiation of keratinocyte progenitor cells, highlighting the role of polyamines in keratinocyte biology.
1 citations
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October 2022 in “Research Square (Research Square)” This study found that melatonin treatment in Cashmere goat kids enhances the density of secondary hair follicles and improves Cashmere quality by regulating the MAPK pathway and reducing cell apoptosis.
4 citations
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February 2016 in “Clinical Pharmacology & Therapeutics” Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
12 citations
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September 2019 in “BioFactors” This study found that Ginkgolide B and bilobalide from Ginkgo biloba increased dermal papilla cell viability and promoted hair follicle growth in mink models by influencing signaling pathways.
2 citations
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May 2008 in “Journal of Clinical Oncology” This study found that patients with unresectable melanoma treated with AZD6244 experienced skin reactions, including depigmentation and papulopustular rashes, in patterns similar to those caused by EGFR inhibitors.
May 2026 in “Animal Bioscience” This study found that m6A-circHECA enhances the differentiation of stem cells into hair follicle lineages in cashmere goats by sequestering miR-449a-5p, boosting LEF1 gene expression, and activating the Wnt/β-catenin pathway.
14 citations
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December 2014 in “PubMed” This study found that melatonin implants in cashmere goats significantly altered the expression pattern and co-expression of miRNAs, suggesting a possible role in inducing a second growth of cashmere.
14 citations
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April 2022 in “Functional & Integrative Genomics” This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study analyzed the formulation and stability of pomade containing peppermint oil and minoxidil, determining that a particular formulation with 1% paraffin yielded optimal physical and stability characteristics for promoting hair growth, making it the best choice among the tested options.
4 citations
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March 2024 in “Cells” This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.
150 citations
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May 1993 in “The journal of cell biology/The Journal of cell biology” This study suggests that mNotch expression plays a significant role in hair follicle differentiation and cell fate selection within the follicle during development.
1 citations
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May 2013 in “Polymer-korea” This study found that using dissolving micro-needles with minoxidil promoted more hair growth in an animal model compared to minoxidil treatment alone or no treatment.