March 2026 in “Journal of Investigative Dermatology” Folliculin slows hair growth, and blocking it might help treat hair loss.
1 citations
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May 2024 in “Animal Biotechnology” In cashmere goats, this study found that reducing miR-361-5p levels activates secondary hair follicle stem cells by upregulating the FOXM1 gene, which in turn stimulates the Wnt/β-catenin pathway, crucial for cashmere fiber morphogenesis.
1 citations
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August 2004 in “Journal of Investigative Dermatology Symposium Proceedings” Adult somatic stem cells could be used for future skin therapies.
38 citations
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December 2006 in “Journal of Investigative Dermatology” Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, distinct molecular mechanisms of action were identified for three drugs used in alopecia areata clinical trials, providing insights for precision medicine and treatment selection.
25 citations
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June 2022 in “Developmental cell” In this study, Hedgehog signaling in dermal papilla fibroblasts was found to accelerate hair growth and induce follicle multiplication in mice via the SCUBE3/TGF-β pathway, with some effects observed in human scalp hair follicles.
In this study, researchers used two dermal papilla spheroid models to investigate hair cycle regression mechanisms and found that the vascular system enhances tissue physiology and gene modulation, while Retinol-based treatments can partially recover tissue degeneration observed over an extended culture period.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
February 2024 in “BMC health services research” This study identified risk of harm and set of competency and skills as key criteria in defining the profession of allied health in Malaysia, highlighting the need for integrated criteria in healthcare policy development.
52 citations
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January 2023 in “Annual Review of Immunology” This review discusses how immune mechanisms contribute to the regeneration and repair of epithelial tissues and highlights their potential role in both disease and therapeutic innovation; it reports no new clinical results.
61 citations
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June 2022 in “Journal of Controlled Release” This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.
15 citations
,
September 2018 in “Frontiers in Plant Science” This study identified that downregulation of the gene BcFLA1 decreases root hair length in Brassica carinata under phosphate-deficient conditions, highlighting its role in root hair elongation.
4 citations
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January 2021 in “in Vivo” This study found that scoparone increased the expression of certain pluripotency-related proteins in dermal papilla cells, suggesting a potential new mechanism for enhancing hair growth.
1 citations
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August 2024 in “Expert Opinion on Drug Safety” This study analyzed data from the FDA Adverse Event Reporting System and found that finasteride had the highest reporting frequency and signal strength for drug-induced erectile dysfunction among 734 drugs, with compound preparations posing higher risks than single ingredients.
January 2026 in “Non-coding RNA Research” This study found that low-passage exosomes from dermal papilla cells enhance hair follicle stem cell proliferation and that miR-218-5p may serve as a potential biomarker and therapeutic target for hair growth.
August 2025 in “Acta Biomaterialia” This study presents a novel hydrogel scaffold made from tilapia collagen, which when activated by ultrasound, reprograms macrophages to promote wound healing, enhance angiogenesis, and stimulate hair follicle regeneration, offering a potential new method for treating inflammatory wounds.
March 2025 in “International Journal of Molecular Sciences” This review explores melatonin's role in hair follicle cycles and its molecular mechanisms that enhance antioxidant capacity and modulate gene expression, offering potential strategies to improve cashmere production and treating human alopecia, according to the authors.
December 2023 in “Animal research and one health” This study investigated circRNA expression in Zhongwei goat skin at different growth stages and found that certain circRNAs, such as circRNA8782 and circRNA3173, may play roles in regulating wool curvature by affecting signaling pathways and fibroblast proliferation.
32 citations
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July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
February 2025 in “Expert Opinion on Drug Safety” This study analyzed adverse event reports from the FDA Adverse Event Reporting System and identified new side effects of topical minoxidil, such as application site acne and cysts, which are not well-documented on product labels, suggesting a need for updated safety information.
January 2018 in “Journal of human virology & retrovirology” This study highlights the need to examine the impact of lifestyle drugs on society, particularly focusing on usage patterns among youth and the general public.
March 2023 in “International Journal of bioprinting” This study found that a bioprinted hydrogel scaffold with zinc and silicon ions significantly activated hair follicle stem cells and enhanced blood vessel formation, promoting hair growth in mouse wound models.
695 citations
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October 2011 in “Cell stem cell” This review discusses the metabolic and physiological mechanisms that maintain hematopoietic stem cell function, particularly focusing on oxygen and energy homeostasis, but it reports no new experimental results.
1 citations
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July 2025 in “Genetics Selection Evolution” In this study, using scRNA-seq, researchers detailed the gene expression and cell differentiation processes in goat fetal horn buds, identifying crucial roles for dermal and epithelial cells in horn initiation and highlighting potential genetic factors involved in horn morphogenesis.
June 2025 in “International Journal of Molecular Sciences” This review compiles current research on the role of long non-coding RNAs in regulating muscle growth and regeneration processes, particularly their influence on Duchenne muscular dystrophy, and reports no new clinical results.
February 2023 in “International Journal of Molecular Sciences” This study found that exosomes derived from dermal papilla cells can enhance the proliferation of hair follicle stem cells by stimulating the LEF1 pathway, offering insights into hair follicle growth regulation.
115 citations
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December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” This review discusses the origins, differentiation, and function of dermal fibroblasts in skin development and healing, reporting no new clinical results.
55 citations
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August 2024 in “Heliyon” This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.
32 citations
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January 2024 in “The Journal of Experimental Medicine” This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.
24 citations
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December 2016 in “Stem Cell Research & Therapy” This study found that P311 triggers transdifferentiation of epidermal stem cells into myofibroblast-like cells via TGFβ1/Smad signaling during wound healing.